Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | MLLT3 | P42568 | 1/20 | 0.31 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20625100 | 0.69 | DYRK1A (0.44) | APPALDH1A3 | |
| SCHEMBL23773808 | 0.65 | MAOB (0.31) | APP | |
| SCHEMBL26751946 | 0.65 | MLLT1 (0.55) | APPKDM4EALDH1A3MLLT3MLLT1 | |
| SCHEMBL1695267 | 0.65 | KDM4E (0.41) | APPKDM4EALDH1A3LMNA | |
| SCHEMBL26009281 | 0.63 | SLC6A2 (0.40) | APPALDH1A3 | |
| SCHEMBL7215441 | 0.61 | SMN1; SMN2 (0.58) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL83839 | 0.59 | ALDH1A1 (0.58) | ALDH1A1KMT2A | |
| SCHEMBL25021843 | 0.58 | APP (0.51) | APPKDM4EALDH1A1HPGDALDH1A3 | |
| SCHEMBL31600503 | 0.58 | PDE10A (0.32) | — | |
| SCHEMBL31599862 | 0.58 | CYP3A4 (0.33) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10730877-B2 | 4-Azaindole compounds | BRISTOL-MYERS SQUIBB COMPANY (US) | 2020-08-04 | — | — | US | disclosed |
| US-6143434-A | HIGH LUMINANCE AND A HIGH LUMINESCENT EFFICIENCY AT A LOW DRIVING VOLTAGE AND HAS EXCELLENT STABILITY IN REPETITIONS OF USE | FUJI PHOTO FILM CO., LTD. (JP) | 2000-11-07 | — | — | US | disclosed |
| EP-0314104-B1 | SILVER HALIDE PHOTOGRAPHIC MATERIALS | FUJI PHOTO FILM CO., LTD. (JP) | 1993-09-15 | — | — | EP | disclosed |
| US-5093222-A | Contrast, negatives | FUJI PHOTO FILM CO., LTD. (JP) | 1992-03-03 | — | — | US | disclosed |
| EP-0314104-A2 | Silver halide photographic materials | FUJI PHOTO FILM CO., LTD. (JP) | 1989-05-03 | — | — | EP | disclosed |
| US-4740455-A | Heat developable light-sensitive material containing polymethine | FUJI PHOTO FILM CO., LTD. (JP) | 1988-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10730877-B2 | 4-Azaindole compounds | TLR7, TLR9, TLR5 | APP 4800/4885KDM4E 1790/4885ALDH1A1 1039/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.