Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 3/20 | 0.31 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8007298 | 0.92 | REN (0.36) | RENKMT2ATSHRBACE1RORC | |
| SCHEMBL4512268 | 0.90 | REN (0.35) | RENKMT2ATSHRRORC | |
| SCHEMBL4510550 | 0.89 | KMT2A (0.38) | RENKMT2ATSHRBACE1RORC | |
| SCHEMBL4502016 | 0.89 | REN (0.34) | RENKMT2ATSHRBACE1 | |
| SCHEMBL13601221 | 0.89 | REN (0.34) | RENKMT2ATSHRBACE1 | |
| SCHEMBL4502114 | 0.89 | REN (0.34) | RENKMT2ATSHRBACE1 | |
| SCHEMBL4508289 | 0.88 | REN (0.36) | RENKMT2ATSHRBACE1SMN1; SMN2 | |
| SCHEMBL8004194 | 0.88 | REN (0.34) | RENKMT2ATSHRBACE1 | |
| SCHEMBL4495264 | 0.88 | REN (0.35) | RENKMT2ATSHR | |
| SCHEMBL4514373 | 0.88 | REN (0.38) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009106599-A2 | SUBSTITUTED PIPERIDINES AS THERAPEUTIC COMPOUNDS | NOVARTIS AG (CH) | 2009-09-03 | — | — | WO | disclosed |