SCHEMBL8007305

SCHEMBL8007305

CCCCC[Sn](N=C=S)(N=C=S)N=C=S

nearest known ligand 0.43

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 1/20 0.43
TSHR P16473 1/20 0.32
THRB P10828 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5897346 0.73 NAAA (0.39) NAAA
SCHEMBL6678825 0.68 NAAA (0.35) NAAA
Hexane SCHEMBL2781361 0.66 TSHR (0.58) NAAATSHRTHRB
Hexane SCHEMBL275660 0.66 TSHR (0.58) NAAATSHRTHRB
Hexane SCHEMBL275309 0.66
Hexane SCHEMBL275495 0.66 TSHR (0.58) NAAATSHRTHRB
Hexane SCHEMBL28077220 0.66 NAAA (0.52) NAAATSHRTHRB
Hexadecane SCHEMBL28842818 0.63 TSHR (0.67) NAAATSHRTHRB
Heptane SCHEMBL28355078 0.63 TSHR (0.67) NAAATSHRTHRB
Dodecane SCHEMBL28138522 0.63 TSHR (0.67) NAAATSHRTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5227309-A C-terminal peptide sequencing method CITY OF HOPE (US) 1993-07-13 US claimed
EP-0823056-A4 METHOD OF CARBOXY TERMINAL PROTEIN OR PEPTIDE SEQUENCING SMITHKLINE BEECHAM CORP (US) 2000-04-19 EP disclosed
US-5968834-A Method of carboxy terminal protein or peptide sequencing SMITHKLINE BEECHAM CORPORATION (US) 1999-10-19 US disclosed
EP-0823056-A1 METHOD OF CARBOXY TERMINAL PROTEIN OR PEPTIDE SEQUENCING SMITHKLINE BEECHAM CORPORATION (US) 1998-02-11 EP disclosed
US-5641685-A Method carboxy terminal protein or peptide sequencing SMITHKLINE BEECHAM CORPORATION (US) 1997-06-24 US disclosed
WO-1996034289-A1 METHOD OF CARBOXY TERMINAL PROTEIN OR PEPTIDE SEQUENCING SMITHKLINE BEECHAM CORPORATION (US) 1996-10-31 WO disclosed
US-5227309-A C-terminal peptide sequencing method CITY OF HOPE (US) 1993-07-13 US disclosed
US-5227309-A C-terminal peptide sequencing method CITY OF HOPE (US) 1993-07-13 US disclosed