Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | NEK2 | P51955 | 1/20 | 0.32 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25275893 | 0.85 | ITGB3 (0.30) | ITGB3ITGA2B | |
| SCHEMBL18820718 | 0.82 | CHRM2 (0.36) | CHRM2CHRM3CYP1A2HIF1ACYP11B1 | |
| SCHEMBL29860723 | 0.81 | CYP11B1 (0.31) | CYP11B1CYP11B2 | |
| SCHEMBL29860703 | 0.77 | CYP1A2 (0.33) | CYP1A2 | |
| SCHEMBL29860996 | 0.77 | — | — | |
| SCHEMBL1753879 | 0.76 | CYP11B1 (0.50) | CHRM2CHRM3TSHRCYP11B1CYP11B2 | |
| SCHEMBL19262304 | 0.73 | CHRM2 (0.39) | CHRM2CHRM3TSHRCYP1A2CYP11B1 | |
| SCHEMBL26822718 | 0.73 | CHRM2 (0.39) | CHRM2CHRM3TSHRCYP1A2CYP3A4 | |
| SCHEMBL18820451 | 0.71 | CHRM2 (0.49) | CHRM2CHRM3CYP11B1CYP11B2NEK2 | |
| SCHEMBL18820460 | 0.71 | CHRM2 (0.38) | CHRM2CHRM3CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000027790-A1 | MUTILIN COMPOUNDS | SMITHKLINE BEECHAM P.L.C. (GB) | 2000-05-18 | — | — | WO | claimed |
| WO-2000027790-A1 | MUTILIN COMPOUNDS | SMITHKLINE BEECHAM P.L.C. (GB) | 2000-05-18 | — | — | WO | disclosed |