Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | P2RX7 | Q99572 | 5/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.51 |
| ▸ | NAMPT | P43490 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.47 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7995663 | 0.99 | CASR (0.62) | CASRSMN1; SMN2POLBKMT2AP2RX7 | |
| SCHEMBL444179 | 0.92 | CASR (0.74) | CASRSMN1; SMN2POLBKMT2AP2RX7 | |
| SCHEMBL8007374 | 0.89 | CASR (0.60) | CASRSMN1; SMN2POLBKMT2AP2RX7 | |
| SCHEMBL8006125 | 0.84 | CASR (0.60) | CASRSMN1; SMN2POLBKMT2AKCNQ2 | |
| Hydrochloric Acid SCHEMBL7995646 | 0.83 | CASR (0.58) | CASRSMN1; SMN2POLBKMT2AKCNQ2 | |
| SCHEMBL11616990 | 0.81 | POLB (0.61) | CASRSMN1; SMN2POLBKMT2ALMNA | |
| SCHEMBL2433439 | 0.78 | CASR (1.00) | CASRSMN1; SMN2LMNAKCNQ2HTT | |
| SCHEMBL11615520 | 0.78 | NAMPT (0.75) | SMN1; SMN2POLBKMT2ANAMPTHTT | |
| SCHEMBL16150572 | 0.75 | CASR (0.67) | CASRSMN1; SMN2POLBKMT2AKCNQ2 | |
| SCHEMBL17512861 | 0.75 | CASR (0.67) | CASRSMN1; SMN2POLBKMT2AKCNQ2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6060484-A | Anti-viral method | ELI LILLY AND COMPANY (US) | 2000-05-09 | — | — | US | disclosed |
| EP-0806205-A2 | Urea, thiourea and guanidine compounds and their use as anti-viral agents | ELI LILLY AND COMPANY (US) | 1997-11-12 | — | — | EP | disclosed |