Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.54 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8007408 | 0.89 | CASR (0.64) | CASRHTTSMN1; SMN2KDM4EKMT2A | |
| SCHEMBL444179 | 0.88 | CASR (0.74) | CASRHTTSMN1; SMN2KDM4EKMT2A | |
| Hydrochloric Acid SCHEMBL7995663 | 0.88 | CASR (0.62) | CASRHTTSMN1; SMN2KDM4EKMT2A | |
| SCHEMBL8006125 | 0.81 | CASR (0.60) | CASRHTTOPRM1SMN1; SMN2KMT2A | |
| Hydrochloric Acid SCHEMBL7995646 | 0.80 | CASR (0.58) | CASRHTTOPRM1SMN1; SMN2KMT2A | |
| SCHEMBL16286227 | 0.77 | KMT2A (0.71) | HTTSMN1; SMN2KDM4EKMT2AMEN1 | |
| SCHEMBL4198398 | 0.77 | TBXAS1 (0.51) | HTTSMN1; SMN2CYP2C9CYP2C19KCNA5 | |
| SCHEMBL2433439 | 0.75 | CASR (1.00) | CASRHTTSMN1; SMN2KCNQ2 | |
| SCHEMBL22926342 | 0.73 | HTT (1.00) | HTTSMN1; SMN2KDM4EKMT2APOLB | |
| SCHEMBL16150572 | 0.72 | CASR (0.67) | CASRHTTSMN1; SMN2KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6060484-A | Anti-viral method | ELI LILLY AND COMPANY (US) | 2000-05-09 | — | — | US | disclosed |
| EP-0806205-A2 | Urea, thiourea and guanidine compounds and their use as anti-viral agents | ELI LILLY AND COMPANY (US) | 1997-11-12 | — | — | EP | disclosed |