Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Methacrylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methacrylic Acid SCHEMBL5680494 | 0.89 | SMN1; SMN2 (0.40) | SMN1; SMN2TDP1ALDH1A1HSD17B10POLB | |
| Methacrylic Acid SCHEMBL51588 | 0.89 | — | — | |
| Methacrylic Acid SCHEMBL5491852 | 0.89 | SMN1; SMN2 (0.40) | SMN1; SMN2TDP1ALDH1A1HSD17B10POLB | |
| Methacrylic Acid SCHEMBL2948016 | 0.89 | SMN1; SMN2 (0.40) | SMN1; SMN2TDP1ALDH1A1HSD17B10POLB | |
| Methacrylic Acid SCHEMBL5445775 | 0.89 | SMN1; SMN2 (0.40) | SMN1; SMN2TDP1ALDH1A1HSD17B10POLB | |
| Methacrylic Acid SCHEMBL5680779 | 0.89 | SMN1; SMN2 (0.40) | SMN1; SMN2TDP1ALDH1A1HSD17B10POLB | |
| Methacrylic Acid SCHEMBL7152497 | 0.89 | SMN1; SMN2 (0.40) | SMN1; SMN2TDP1ALDH1A1HSD17B10POLB | |
| Methacrylic Acid SCHEMBL2592759 | 0.89 | SMN1; SMN2 (0.40) | SMN1; SMN2TDP1ALDH1A1HSD17B10POLB | |
| Methacrylic Acid SCHEMBL2951300 | 0.89 | SMN1; SMN2 (0.40) | SMN1; SMN2TDP1ALDH1A1HSD17B10POLB | |
| Methacrylic Acid SCHEMBL2955218 | 0.89 | SMN1; SMN2 (0.40) | SMN1; SMN2TDP1ALDH1A1HSD17B10POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000035677-A1 | INKJET PRINTING MEDIUM COMPRISING MULTIPLE COATINGS | PPG INDUSTRIES OHIO, INC. (US) | 2000-06-22 | — | — | WO | disclosed |