Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 5/20 | 0.68 |
| ▸ | CNR1 | P21554 | 4/20 | 0.68 |
| ▸ | ACHE | P22303 | 4/20 | 0.68 |
| ▸ | PDE5A | O76074 | 10/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.62 |
| ▸ | GMNN | O75496 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.62 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6767172 | 0.91 | CNR2 (0.68) | CNR2CNR1ACHEPDE5ACYP1A2 | |
| SCHEMBL6764379 | 0.83 | PDE5A (0.62) | CNR2CNR1ACHEPDE5ACYP1A2 | |
| SCHEMBL3076501 | 0.79 | PDE5A (0.66) | CNR2CNR1ACHEPDE5ACYP1A2 | |
| SCHEMBL6764408 | 0.77 | CNR2 (0.65) | CNR2CNR1ACHEPDE5ACYP1A2 | |
| SCHEMBL187837 | 0.77 | PDE5A (1.00) | CNR2CNR1ACHEPDE5ACYP1A2 | |
| SCHEMBL29352550 | 0.77 | PDE5A (1.00) | CNR2CNR1ACHEPDE5ACYP1A2 | |
| SCHEMBL12092607 | 0.75 | CNR2 (0.76) | CNR2CNR1ACHEPDE5ACYP1A2 | |
| Bendazac SCHEMBL25979 | 0.75 | CNR2 (0.70) | CNR2CNR1ACHEPDE5ACYP1A2 | |
| SCHEMBL16772288 | 0.75 | CYP1A2 (0.70) | CNR2CNR1ACHEPDE5ACYP1A2 | |
| Bendazac SCHEMBL30299455 | 0.75 | CNR2 (0.70) | CNR2CNR1ACHEPDE5ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000027394-A1 | ACTIVATORS OF SOLUBLE GUANYLATE CYCLASE | UNIVERSITY COLLEGE LONDON (GB) | 2000-05-18 | — | — | WO | disclosed |