Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.50 |
| ▸ | IDH1 | O75874 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | AGXT | P21549 | 2/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | MIF | P14174 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3300303 | 0.79 | TAAR1 (0.60) | TAAR1IDH1IDO1AGXTALDH1A1 | |
| SCHEMBL20257528 | 0.76 | TAAR1 (0.49) | TAAR1IDH1IDO1AGXTACHE | |
| SCHEMBL2352229 | 0.74 | CALM1 (0.52) | TAAR1ALDH1A1 | |
| SCHEMBL16191188 | 0.74 | TAAR1 (0.52) | TAAR1IDH1IDO1AGXTACHE | |
| SCHEMBL16191018 | 0.73 | TAAR1 (0.50) | TAAR1IDH1IDO1AGXTACHE | |
| SCHEMBL3298408 | 0.73 | CALM1 (0.57) | TAAR1IDH1IDO1AGXTALDH1A1 | |
| SCHEMBL18674018 | 0.72 | IDH1 (0.51) | TAAR1IDH1IDO1AGXTACHE | |
| SCHEMBL19619123 | 0.72 | TAAR1 (0.49) | TAAR1IDH1IDO1AGXTACHE | |
| SCHEMBL19367314 | 0.72 | TAAR1 (0.49) | TAAR1IDH1IDO1AGXTACHE | |
| SCHEMBL7929350 | 0.71 | TAAR1 (0.52) | TAAR1IDO1AGXTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009099582-A2 | COMPOSITIONS AND METHODS FOR TREATING DIABETES USING LISOFYLLINE ANALOGS AND ISLET NEOGENESIS ASSOCIATED PEPTIDE | DIAKINE THERAPEUTICS, INC. (US) | 2009-08-13 | — | — | WO | disclosed |