SCHEMBL8007900

SCHEMBL8007900

CC(=O)OCC[C@@H](C)CCC=O.CCC[C@H](C)CCO

nearest known ligand 0.56

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 2/20 0.56
ALDH1A1 P00352 3/20 0.41
TSHR P16473 2/20 0.33
PTPN1 P18031 1/20 0.32
PRKCA P17252 1/20 0.31
SOAT2 O75908 1/20 0.30
SOAT1 P35610 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25557425 0.87 ALOX15 (0.71) ALOX15ALDH1A1TSHRPTPN1
SCHEMBL8007782 0.87 ALOX15 (0.71) ALOX15ALDH1A1TSHRPTPN1
SCHEMBL7553169 0.82 ALOX15 (0.61) ALOX15ALDH1A1TSHRPTPN1
SCHEMBL15542057 0.82 ALOX15 (0.61) ALOX15ALDH1A1TSHRPTPN1
Citronellyl Acetate SCHEMBL4623480 0.80 ALOX15 (0.87) ALOX15ALDH1A1TSHRPTPN1
SCHEMBL9333797 0.77
Citronellyl Acetate SCHEMBL3666360 0.76 ALOX15 (0.73) ALOX15ALDH1A1TSHRPTPN1
SCHEMBL233139 0.75
SCHEMBL14817185 0.75
SCHEMBL7552905 0.75 ALOX15 (0.70) ALOX15ALDH1A1TSHRPTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2000024358-A2 SYNTHESIS AND USES OF THIOPENTONE ENANTIOMERS THE UNIVERSITY OF SYDNEY (AU) 2000-05-04 WO disclosed