⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5673789 | 0.97 | TSHR (0.39) | — | |
| SCHEMBL3714824 | 0.94 | — | — | |
| SCHEMBL3715959 | 0.88 | — | — | |
| SCHEMBL4606679 | 0.76 | CTSC (0.31) | — | |
| SCHEMBL4605391 | 0.76 | NSD2 (0.32) | — | |
| SCHEMBL4516934 | 0.76 | DPP9 (0.42) | — | |
| SCHEMBL28099479 | 0.73 | TSHR (0.42) | — | |
| SCHEMBL1911324 | 0.73 | — | — | |
| Cycloleucine SCHEMBL21462057 | 0.73 | NSD2 (0.50) | — | |
| Cycloleucine SCHEMBL8495 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0675133-B1 | 13-Substituted milbemycin derivatives, their preparation and use | SANKYO CO (JP) | 2000-01-12 | — | — | EP | disclosed |
| US-5614470-A | AGRICULTURAL ANTHELMINTIC, ACARICIDE, INSECTICIDE | SANKYO COMPANY, LIMITED (JP) | 1997-03-25 | — | — | US | disclosed |
| EP-0675133-A1 | 13-Substituted milbemycin derivatives, their preparation and use | SANKYO COMPANY LIMITED (JP) | 1995-10-04 | — | — | EP | disclosed |