Cycloleucine

Cycloleucine

SCHEMBL8495

NC1(C(=O)O)CCCC1

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cycloleucine SCHEMBL21462057 1.00 NSD2 (0.50)
Cycloleucine SCHEMBL3164459 0.97 NSD2 (0.48)
Cycloleucine SCHEMBL1704308 0.97 NSD2 (0.48)
SCHEMBL59793 0.97 NSD2 (0.48)
Cycloleucine SCHEMBL3674853 0.97 NSD2 (0.48)
SCHEMBL744894 0.97 NSD2 (0.48)
SCHEMBL62221 0.97 NSD2 (0.48)
SCHEMBL21423145 0.97 NSD2 (0.48)
Cycloleucine SCHEMBL1711763 0.97 NSD2 (0.48)
SCHEMBL15095885 0.97 NSD2 (0.48)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 9233 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122084906-A Plasma metabolism marker for early diagnosis or prediction of gestational diabetes mellitus and application thereof 2026-05-26 CN claimed
US-12630588-B2 Bicyclic peptide ligands specific for CD137 BICYCLETX LIMITED (GB) 2026-05-19 US claimed
WO-2026099897-A1 NOVEL LINKERS AND ITS PREPARATION METHODS THEREOF ZYDUS LIFESCIENCES LIMITED (IN) 2026-05-15 WO claimed
US-20260124313-A1 SITE-SPECIFIC COVALENT LIGATION OF HUMAN SERUM ALBUMIN UNIV CALIFORNIA (US) 2026-05-07 US claimed
US-12600699-B2 Thiosemicarbazates and uses thereof THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2026-04-14 US claimed
US-20260098072-A1 METHODS OF STIMULATING APPETITE AND/OR INCREASING BODY WEIGHT USING NON-NATURALLY OCCURRING MELANOCORTIN RECEPTOR ANTAGONIST ANALOGS ENDEVICA BIO INC (US) 2026-04-09 US claimed
US-20260060962-A1 METHODS AND AGENTS THAT STIMULATE MITOCHONDRIAL TURNOVER FOR TREATING DISEASE CAPACITY BIO INC (US) 2026-03-05 US claimed
US-12551535-B2 Peptide pharmaceuticals for insulin resistance MEDERIS DIABETES, LLC (US) 2026-02-17 US claimed
EP-4127157-B1 MODIFIED DIPEPTIDE CLEAVASES, USES THEREOF AND RELATED KITS ENCODIA INC (US) 2026-02-11 EP claimed
EP-3967714-B1 VINYL ALCOHOL-AMINO ACID ESTER COPOLYMER, THEIR PREPARATION AND USES SEKISUI CHEMICAL CO LTD (JP) 2026-01-07 EP claimed
US-4759866-A Mixture of alkali metal salts and 1-amino-cyclopentane-carboxylic acid and derivatives or its precursor as gas scrubber EXXON RESEARCH AND ENGINEERING COMPANY (US) 1988-07-26 US claimed
EP-0245961-A1 Acid gas scrubbing composition and process EXXON RESEARCH AND ENGINEERING COMPANY (US) 1987-11-19 EP claimed
US-4436910-A SAPONIFICATION DEGUSSA AKTIENGESELLSCHAFT (DE) 1984-03-13 US claimed
US-4427762-A DEVELOPMENT WITH ALKALINE DEVELOPER MIXTURE KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1984-01-24 US claimed
EP-0036713-B1 ANGIOTENSIN CONVERTING ENZYME INHIBITORS UNIVERSITY OF MIAMI (US) 1984-01-18 EP claimed
EP-0082015-A1 Method of forming an image with a photographic cuprous halide material KONICA CORPORATION (JP) 1983-06-22 EP claimed
EP-0024172-B1 ANTITUMOR AND IMMUNOSUPPRESSIVE 4-CARBAMOYLIMIDAZOLIUM-5-OLATE DERIVATIVES, PHARMACEUTICAL COMPOSITION AND PRODUCTION THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1983-05-11 EP claimed
EP-0036713-A2 Angiotensin converting enzyme inhibitors UNIVERSITY OF MIAMI (US) 1981-09-30 EP claimed
US-3981915-A Amides of 1-aminocyclopentane carboxylic acid AMERICAN HOME PRODUCTS CORPORATION (US) 1976-09-21 US claimed
US-3976692-A ANALGESIC AMERICAN HOME PRODUCTS CORPORATION (US) 1976-08-24 US claimed