Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 2/20 | 0.45 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 4/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 4/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6104432 | 0.77 | GRIN1 (0.45) | GRIN1GRIN2ATSHRHTR2ATAAR1 | |
| Water SCHEMBL28973052 | 0.70 | MTOR (0.62) | GRIN1GRIN2ATSHRHTR2ATAAR1 | |
| SCHEMBL1908636 | 0.69 | TAAR1 (0.64) | GRIN1GRIN2AHTR2ATAAR1KDM4E | |
| SCHEMBL3952853 | 0.69 | PBRM1 (0.47) | TSHRTRPA1HTR2ATAAR1KDM4E | |
| Water SCHEMBL5164513 | 0.69 | PBRM1 (0.47) | TSHRTRPA1HTR2ATAAR1KDM4E | |
| SCHEMBL27366623 | 0.69 | AOC3 (0.64) | GRIN1GRIN2AHTR2ATAAR1KDM4E | |
| SCHEMBL3449112 | 0.67 | MTOR (0.46) | TSHRTRPA1KDM4EL3MBTL1MTOR | |
| SCHEMBL581278 | 0.67 | MAPT (0.52) | TSHRKDM4EMEN1KMT2ACYP3A4 | |
| SCHEMBL2308839 | 0.67 | MAPT (0.52) | GRIN1GRIN2AHTR2ATAAR1KDM4E | |
| SCHEMBL9778091 | 0.67 | TSHR (0.44) | TSHRTRPA1HTR2ATAAR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6060484-A | Anti-viral method | ELI LILLY AND COMPANY (US) | 2000-05-09 | — | — | US | disclosed |
| EP-0806205-A2 | Urea, thiourea and guanidine compounds and their use as anti-viral agents | ELI LILLY AND COMPANY (US) | 1997-11-12 | — | — | EP | disclosed |