Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 13/20 | 0.58 |
| ▸ | MEN1 | O00255 | 6/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.58 |
| ▸ | GAA | P10253 | 6/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8007429 | 0.81 | CYP1A2 (0.46) | MAPTMEN1KMT2AGAASMN1; SMN2 | |
| SCHEMBL7997471 | 0.79 | MAPT (0.50) | MAPTMEN1KMT2AGAASMN1; SMN2 | |
| SCHEMBL8612145 | 0.79 | MAPT (0.63) | MAPTMEN1KMT2AGAASMN1; SMN2 | |
| SCHEMBL6177707 | 0.79 | SMN1; SMN2 (0.51) | MAPTMEN1KMT2AGAASMN1; SMN2 | |
| SCHEMBL6967259 | 0.78 | FGFR4 (0.48) | MAPTMEN1KMT2AGAASMN1; SMN2 | |
| SCHEMBL6176987 | 0.77 | FGFR4 (0.49) | MAPTMEN1KMT2AGAASMN1; SMN2 | |
| SCHEMBL8008037 | 0.76 | SMN1; SMN2 (0.54) | MAPTMEN1KMT2AGAASMN1; SMN2 | |
| SCHEMBL8674019 | 0.73 | GAA (0.42) | MAPTMEN1KMT2AGAASMN1; SMN2 | |
| SCHEMBL6176381 | 0.73 | ALDH1A1 (0.50) | MAPTMEN1KMT2AGAASMN1; SMN2 | |
| SCHEMBL9034789 | 0.73 | ALDH1A1 (0.63) | MAPTMEN1KMT2AGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6165941-A | Substituted 2-phenylpyridines | BASF AKTIENGESELLSCHAFT (DE) | 2000-12-26 | — | — | US | disclosed |
| EP-0708769-A1 | SUBSTITUTED 2-FUSED PHENYLPYRIDINES WITH HERBICIDAL ACTIVITY | BASF AKTIENGESELLSCHAFT (DE) | 1996-05-01 | — | — | EP | disclosed |
| WO-1995002590-A2 | SUBSTITUTED 2-FUSED PHENYLPYRIDINES WITH HERBICIDAL ACTIVITIES | BASF AKTIENGESELLSCHAFT (DE) | 1995-01-26 | — | — | WO | disclosed |