SCHEMBL8008137

SCHEMBL8008137

COc1ccc(/C=C(\C(=O)O)c2ccc(OC)cc2)cc1

nearest known ligand 0.78

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 4/20 0.78
ALDH1A1 P00352 3/20 0.60
MEN1 O00255 1/20 0.60
KMT2A Q03164 1/20 0.60
MAPT P10636 2/20 0.59
KDM4E B2RXH2 1/20 0.59
HPGD P15428 1/20 0.59
AKR1C1 Q04828 2/20 0.56
LMNA P02545 1/20 0.56
CA1 P00915 1/20 0.55
CA2 P00918 1/20 0.55
PTGS2 P35354 2/20 0.54
F3 P13726 1/20 0.53
HTT P42858 1/20 0.53
AKR1C2 P52895 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4539035 1.00 AKR1C3 (0.78) AKR1C3ALDH1A1MEN1KMT2AMAPT
SCHEMBL28674818 0.94 AKR1C3 (0.70) AKR1C3ALDH1A1MEN1KMT2AMAPT
SCHEMBL16968119 0.94 AKR1C3 (0.70) AKR1C3ALDH1A1MEN1KMT2AMAPT
SCHEMBL16968120 0.94 AKR1C3 (0.70) AKR1C3ALDH1A1MEN1KMT2AMAPT
SCHEMBL4365603 0.93 ALDH1A1 (0.70) AKR1C3ALDH1A1MEN1KMT2AMAPT
SCHEMBL4365600 0.93 ALDH1A1 (0.70) AKR1C3ALDH1A1MEN1KMT2AMAPT
SCHEMBL13950671 0.93 ALDH1A1 (0.70) AKR1C3ALDH1A1MEN1KMT2AMAPT
SCHEMBL9351937 0.92 AKR1C3 (0.68) AKR1C3ALDH1A1MEN1KMT2AMAPT
SCHEMBL18039144 0.92 AKR1C3 (0.68) AKR1C3ALDH1A1MEN1KMT2AMAPT
SCHEMBL18039143 0.92 AKR1C3 (0.68) AKR1C3ALDH1A1MEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5098952-A Acrylate copolymers with hydroxyalkyl acrylate or methacrylate for high glass transition temperature S. C. JOHNSON & SON, INC. (US) 1992-03-24 US claimed
EP-0968241-A1 ACRYLIC POWDER COATING INCLUDING HIGH HOMOPOLYMER GLASS TRANSITION TEMPERATURE CYCLIC (METH)ACRYLATE MONOMER AS VISCOSITY MODIFIER RHODIA INC. (US) 2000-01-05 EP disclosed
WO-1998042765-A1 ACRYLIC POWDER COATING INCLUDING HIGH HOMOPOLYMER GLASS TRANSITION TEMPERATURE CYCLIC (METH)ACRYLATE MONOMER AS VISCOSITY MODIFIER RHODIA INC. (US) 1998-10-01 WO disclosed
US-5663207-A ADMINISTERING TO INHIBIT DEVELOPMENT OF BREAST TUMOR RESEARCH CORPORATION TECHNOLOGIES (US) 1997-09-02 US disclosed
US-5397802-A Gem-dichlorocyclopropanes as antitumor agents RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 1995-03-14 US disclosed
US-5098956-A Acrylate copolymers with hydroxyalkyl acrylate or methacrylate for high glass transition temperature S.C. JOHNSON & SON, INC. (US) 1992-03-24 US disclosed
US-5098952-A Acrylate copolymers with hydroxyalkyl acrylate or methacrylate for high glass transition temperature S. C. JOHNSON & SON, INC. (US) 1992-03-24 US disclosed
EP-0212705-B1 RECORD CARRIER FOR AN ELECTRON BEAM Philips Patentverwaltung GmbH (DE) 1990-05-02 EP disclosed
US-4921934-A AUTOPOLYMERIZATION, AGRAFT POLYMER OF UNSATURATED CARBOXYLIC ACID WITH POLYLACTONE S. C. JOHNSON & SON, INC. (US) 1990-05-01 US disclosed
EP-0321913-A2 Alkali-soluble polymer and process for producing same S.C. JOHNSON & SON, INC. (US) 1989-06-28 EP disclosed
EP-0212705-A1 Record carrier for an electron beam Philips Patentverwaltung GmbH (DE) 1987-03-04 EP disclosed
US-4572803-A ENHANCED THERMAL, CHEMICAL AND PHYSICAL STABILITY ASAHI DOW LIMITED (JP) 1986-02-25 US disclosed
US-4443380-A Organic europlum salt phosphor ASAHI-DOW LIMITED (JP) 1984-04-17 US disclosed
US-4247597-A Electroscopic carrier particles having a carboxylic acid surface treatment PITNEY BOWES, INC. (US) 1981-01-27 US disclosed