Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27199826 | 0.89 | KDM4E (0.54) | KDM4EALDH1A1MEN1KMT2AHTT | |
| SCHEMBL819986 | 0.81 | L3MBTL1 (0.53) | KDM4EALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL3865671 | 0.79 | L3MBTL1 (0.47) | ALDH1A1GAAL3MBTL1 | |
| SCHEMBL866542 | 0.78 | KDM4E (0.60) | KDM4EALDH1A1MEN1KMT2AHTT | |
| SCHEMBL6851313 | 0.78 | MAPT (0.43) | KDM4EALDH1A1MEN1KMT2AHTT | |
| SCHEMBL4828682 | 0.77 | KCNA3 (0.52) | KDM4EALDH1A1GAASMN1; SMN2TDP1 | |
| SCHEMBL17237835 | 0.76 | NR5A1 (0.53) | GAAL3MBTL1 | |
| SCHEMBL17237799 | 0.76 | NR5A1 (0.53) | GAAL3MBTL1 | |
| SCHEMBL17555973 | 0.76 | L3MBTL1 (0.50) | GAAL3MBTL1 | |
| SCHEMBL17556007 | 0.76 | L3MBTL1 (0.50) | GAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6147136-A | CURING; FREE RADICAL OR CATIONIC POLYMERIZATION; CEMENTING | ESPE DENTAL AG (DE) | 2000-11-14 | — | — | US | disclosed |
| US-6075068-A | RAPID POLYMERIZATION PROCESS, LEADING TO PARTIALLY OR FULLY CURED MATERIALS WHICH EXHIBIT LITTLE VOLUME SHRINKAGE, LITTLE ABRASION TENDENCY AND GOOD MECHANICAL PROPERTIES | ESPE DENTAL AG (DE) | 2000-06-13 | — | — | US | disclosed |