SCHEMBL80082

SCHEMBL80082

BrCCCC1CCCCC1

nearest known ligand 0.56

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.56
SIGMAR1 Q99720 4/20 0.52
EPHX1 P07099 1/20 0.36
HPGD P15428 1/20 0.34
KDM5A P29375 2/20 0.34
PHF8 Q9UPP1 2/20 0.34
KDM2A Q9Y2K7 2/20 0.34
KDM4C Q9H3R0 1/20 0.34
KDM4A O75164 1/20 0.34
CEL P19835 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11023325 1.00 CYP1A2 (0.56) CYP1A2SIGMAR1EPHX1HPGDKDM5A
SCHEMBL11021457 1.00 CYP1A2 (0.56) CYP1A2SIGMAR1EPHX1HPGDKDM5A
SCHEMBL11019093 1.00 CYP1A2 (0.56) CYP1A2SIGMAR1EPHX1HPGDKDM5A
Bromide SCHEMBL19330051 0.97 CYP1A2 (0.54) CYP1A2SIGMAR1EPHX1HPGDKDM5A
SCHEMBL3691804 0.97
SCHEMBL11154618 0.92 SIGMAR1 (0.56) CYP1A2SIGMAR1EPHX1KDM5APHF8
SCHEMBL79050 0.92 SIGMAR1 (0.56) CYP1A2SIGMAR1EPHX1KDM5APHF8
SCHEMBL19922821 0.92
SCHEMBL12375433 0.91 CYP1A2 (0.48) CYP1A2SIGMAR1EPHX1KDM5APHF8
SCHEMBL7619522 0.90 SIGMAR1 (0.60) CYP1A2SIGMAR1EPHX1KDM5APHF8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 328 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12617756-B2 Substituted imidazolidines for treating a RNA virus infection ABIVAX (FR) 2026-05-05 US disclosed
US-12612380-B2 Non-lysosomal glucosylceramidase inhibitors and uses thereof ALECTOS THERAPEUTICS 1NC (CA) 2026-04-28 US disclosed
EP-3966199-B1 NON-LYSOSOMAL GLUCOSYLCERAMIDASE INHIBITORS AND USES THEREOF ALECTOS THERAPEUTICS INC (CA) 2026-03-18 EP disclosed
US-12528773-B2 Non-lysosomal glucosylceramidase inhibitors and uses thereof ALECTOS THERAPEUTICS INC. (CA) 2026-01-20 US disclosed
EP-4647432-A1 AROMATIC COMPOUND, ORGANIC SEMICONDUCTOR LAYER, AND ORGANIC THIN FILM TRANSISTOR Tosoh Corporation (JP) 2025-11-12 EP disclosed
CN-112703183-B Aryl-N-aryl derivatives for the treatment of RNA viral infections ABIVAX公司 2025-06-10 CN disclosed
US-12247018-B2 Aryl-n-aryl derivatives for treating a RNA virus infection ABIVAX (FR) 2025-03-11 US disclosed
CN-114174263-B Non-lysosomal glucosylceramidase inhibitors and uses thereof 阿勒克图治疗公司 2025-01-10 CN disclosed
WO-2024162378-A1 AROMATIC COMPOUND, ORGANIC SEMICONDUCTOR LAYER, AND ORGANIC THIN FILM TRANSISTOR 東ソー株式会社 2024-08-08 WO disclosed
CN-110770214-B Heterocyclic P2X7 antagonists 布雷耶疗法有限公司 2024-03-29 CN disclosed
WO-1998005327-A1 SUBSTITUTED AROMATIC COMPOUNDS RHONE-POULENC RORER PHARMACEUTICALS INC. (US) 1998-02-12 WO disclosed
WO-1997048697-A1 SUBSTITUTED AZABICYLIC COMPOUNDS AND THEIR USE AS INHIBITORS OF THE PRODUCTION OF TNF AND CYCLIC AMP PHOSPHODIESTERASE RHONE-POULENC RORER LIMITED (GB) 1997-12-24 WO disclosed
EP-0447188-B1 7-Oxabicycloheptane imidazole prostaglandin analogs useful in the treatment of thrombotic and vasospastic diseases SQUIBB & SONS INC (US) 1995-06-28 EP disclosed
EP-0447188-A2 7-Oxabicycloheptane imidazole prostaglandin analogs useful in the treatment of thrombotic and vasospastic diseases E.R. SQUIBB & SONS, INC. (US) 1991-09-18 EP disclosed
EP-0403090-A1 7-oxabicycloheptane imidazole prostaglandin analogs useful in the treatment of thrombotic and vasopastic disease E.R. SQUIBB & SONS, INC. (US) 1990-12-19 EP disclosed
US-4977174-A Anticoagulants, antischemic agents E. R. SQUIBB & SONS, INC. (US) 1990-12-11 US disclosed
EP-0046961-B1 EPOXY-CYCLOALKYLALKANECARBOXYLIC ACIDS, PROCESS FOR THEIR PREPARATION, THEIR USE AND MEDICAMENTS CONTAINING THEM Byk Gulden Lomberg Chemische Fabrik GmbH (DE) 1985-02-13 EP disclosed
US-4430339-A PROPHYLAXIS, METABOLISM, GLUCOSE, FATS, HYPOGLYCEMIC AGENTS BYK GULDEN LOMBERG CHEMISCHE FABRIK GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1984-02-07 US disclosed
WO-1982000822-A1 SUBSTITUTED OXIRANECARBOXYLIC ACIDS,THEIR PREPARATION AND THEIR USE AS MEDICAMENTS EISTETTER K 1982-03-18 WO disclosed
EP-0046961-A1 Epoxy-cycloalkylalkanecarboxylic acids, process for their preparation, their use and medicaments containing them Byk Gulden Lomberg Chemische Fabrik GmbH (DE) 1982-03-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12528773-B2 Non-lysosomal glucosylceramidase inhibitors and uses thereof GBA1, GBA2, GAA CYP1A2 2573/4885SIGMAR1 745/4885EPHX1 1134/4885
US-12617756-B2 Substituted imidazolidines for treating a RNA virus infection NSUN2, NSUN3, ZC3HAV1 CYP1A2 2047/4885SIGMAR1 304/4885EPHX1 3988/4885
US-12612380-B2 Non-lysosomal glucosylceramidase inhibitors and uses thereof GBA1, GBA2, MAN2B1 CYP1A2 2435/4885SIGMAR1 1034/4885EPHX1 1284/4885
US-12247018-B2 Aryl-n-aryl derivatives for treating a RNA virus infection CRKL, VRK2, FRK CYP1A2 1897/4885SIGMAR1 577/4885EPHX1 4649/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.