SCHEMBL8008239

SCHEMBL8008239

CC(C)[C@](O)(CCc1ccc(N)cc1)CC(=O)O

nearest known ligand 0.44

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SLC13A5 Q86YT5 11/20 0.44
GFER P55789 1/20 0.38
MAOB P27338 3/20 0.38
MAOA P21397 2/20 0.38
S1PR4 O95977 1/20 0.38
S1PR1 P21453 1/20 0.38
S1PR3 Q99500 1/20 0.38
S1PR5 Q9H228 1/20 0.38
ITGB1 P05556 3/20 0.38
ITGA5 P08648 3/20 0.38
ESRRG P62508 1/20 0.37
ITGB3 P05106 2/20 0.36
ITGAV P06756 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7998719 0.86 SLC13A5 (0.46) SLC13A5
SCHEMBL7998721 0.86 SLC13A5 (0.46) SLC13A5
SCHEMBL6695081 0.86 SLC13A5 (0.49) SLC13A5
SCHEMBL6302904 0.86 SLC13A5 (0.49) SLC13A5
SCHEMBL6692391 0.86 SLC13A5 (0.49) SLC13A5
SCHEMBL6297597 0.85 SLC13A5 (0.44) SLC13A5S1PR1
SCHEMBL6691221 0.85 SLC13A5 (0.44) SLC13A5S1PR1
SCHEMBL6692548 0.85 SLC13A5 (0.44) SLC13A5S1PR1
Acetamide SCHEMBL7635491 0.84 SLC13A5 (0.44) SLC13A5
SCHEMBL6297833 0.82 SLC13A5 (0.49) SLC13A5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6046355-A TOLUENE-4-THIOSULFONIC ACID S-ESTERS AS CHEMICAL INTERMEDIATES FOR VIRICIDES AND ASPARTYL PROTEASE INHIBITORS; AIDS WARNER-LAMBERT COMPANY (US) 2000-04-04 US disclosed
EP-0935597-A2 DIHYDROPYRONES WITH IMPROVED ANTIVIRAL ACTIVITY WARNER-LAMBERT COMPANY (US) 1999-08-18 EP disclosed
WO-1998019997-A2 DIHYDROPYRONES WITH IMPROVED ANTIVIRAL ACTIVITY WARNER-LAMBERT COMPANY (US) 1998-05-14 WO disclosed