Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5158290 | 0.91 | TSHR (0.47) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL7736939 | 0.91 | TSHR (0.47) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL3895145 | 0.87 | MEN1 (0.55) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL11593290 | 0.87 | TSHR (0.43) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL1161497 | 0.84 | LMNA (0.52) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL27580020 | 0.84 | LMNA (0.52) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL9353888 | 0.84 | TSHR (0.41) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL350840 | 0.84 | TSHR (0.53) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL6666676 | 0.84 | — | — | |
| SCHEMBL11217212 | 0.83 | MEN1 (0.50) | TSHRMAPK1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1051446-A1 | ISOINDOLINE PIGMENT HAVING IMPROVED LOW SHEAR DISPERSIBILITY | Ciba SC Holding AG (CH) | 2000-11-15 | — | — | EP | disclosed |
| US-6143067-A | Isoindoline pigment having improved low shear dispersibility | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2000-11-07 | — | — | US | disclosed |
| WO-1999038920-A1 | ISOINDOLINE PIGMENT HAVING IMPROVED LOW SHEAR DISPERSIBILITY | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 1999-08-05 | — | — | WO | disclosed |