SCHEMBL8008522

SCHEMBL8008522

CCCCCCCCCCC#CC#CCCCCCCCCC(=O)OC(=O)CCCCCCCCC#CC#CCCCCCCCCCC

nearest known ligand 0.68

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
HMGCR P04035 6/20 0.68
PTPN7 P35236 4/20 0.62
SELP P16109 1/20 0.55
DGKA P23743 1/20 0.50
RECQL P46063 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
LMNA P02545 2/20 0.47
PAM P19021 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1903371 0.92 PTPN7 (0.66) HMGCRPTPN7DGKARECQLTDP1
SCHEMBL9795755 0.89 HMGCR (0.55) HMGCRPTPN7SELPDGKARECQL
SCHEMBL940458 0.87 HMGCR (0.66) HMGCRPTPN7SELPDGKA
SCHEMBL940491 0.87 HMGCR (0.66) HMGCRPTPN7SELPDGKA
SCHEMBL21544536 0.87 HMGCR (0.66) HMGCRPTPN7SELPDGKA
SCHEMBL27448423 0.86 DGKA (0.64) DGKATDP1LMNAPAM
SCHEMBL12805568 0.86 DGKA (0.64) DGKATDP1LMNAPAM
SCHEMBL28721461 0.86 HMGCR (0.64) HMGCRPTPN7SELPDGKALMNA
SCHEMBL6530433 0.86 HMGCR (0.64) HMGCRPTPN7SELPDGKARECQL
SCHEMBL4754044 0.84 DGKA (0.61) DGKATDP1LMNAPAM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6013206-A Process for the formation of high aspect ratio lipid microtubules THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2000-01-11 US disclosed
WO-1999060095-A2 FORMATION AND METALLIZATION OF HIGH ASPECT RATIO LIPID MICROTUBULES THE GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY OF THE NAVY (US) 1999-11-25 WO disclosed
US-5663387-A Liposomes containing polymerized lipids for non-covalent immobilization of proteins and enzymes THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 1997-09-02 US disclosed
US-5466467-A Liposomes containing polymerized lipids for non-covalent immobilization of proteins and enzymes THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 1995-11-14 US disclosed
US-4933114-A Polyacetylenic lipids, radiation-sensitive compositions, photographic elements and processes relating to same EASTMAN KODAK COMPANY (US) 1990-06-12 US disclosed
EP-0057207-B1 PHOTOGRAPHIC ELEMENTS EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1985-04-17 EP disclosed
EP-0057207-A4 PHOTOGRAPHIC ELEMENTS. EASTMAN KODAK CO (US) 1982-12-20 EP disclosed
EP-0057207-A1 PHOTOGRAPHIC ELEMENTS. EASTMAN KODAK CO (US) 1982-08-11 EP disclosed
WO-1982000532-A1 POLYACETYLENIC LIPIDS,RADIATION-SENSITIVE COMPOSITIONS,PHOTOGRAPHIC ELEMENTS AND PROCESSES EASTMAN KODAK CO (US) 1982-02-18 WO disclosed
US-4314021-A Photographic element having a layer of lipid compound EASTMAN KODAK COMPANY (US) 1982-02-02 US disclosed