Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 6/20 | 0.45 |
| ▸ | HCRTR2 | O43614 | 6/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | RBP4 | P02753 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | CCR2 | P41597 | 2/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.37 |
| ▸ | KDM5A | P29375 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16302039 | 0.88 | HDAC3 (0.48) | HCRTR1HCRTR2 | |
| SCHEMBL7955000 | 0.88 | HDAC3 (0.48) | HCRTR1HCRTR2 | |
| SCHEMBL12428623 | 0.88 | HDAC3 (0.48) | HCRTR1HCRTR2 | |
| SCHEMBL7959667 | 0.85 | ALDH1A1 (0.43) | HCRTR1HCRTR2FFAR4ACACBHRH3 | |
| SCHEMBL12428624 | 0.85 | ALDH1A1 (0.43) | HCRTR1HCRTR2FFAR4ACACBHRH3 | |
| SCHEMBL15137215 | 0.75 | FFAR4 (0.44) | HCRTR1HCRTR2FFAR4DPP4DPP7 | |
| SCHEMBL15137028 | 0.75 | HCRTR1 (0.45) | HCRTR1HCRTR2FFAR4DPP4DPP7 | |
| SCHEMBL16580873 | 0.75 | HCRTR1 (0.44) | HCRTR1HCRTR2ACACB | |
| SCHEMBL1364669 | 0.75 | HDAC3 (0.47) | CCR2 | |
| SCHEMBL1365213 | 0.75 | HDAC3 (0.47) | CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009137503-A1 | HDAC INHIBITORS AND USES THEREOF | ENVIVO PHARMACEUTICALS, INC. (US) | 2009-11-12 | — | — | WO | disclosed |