Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ILK | Q13418 | 3/20 | 0.40 |
| ▸ | F2RL3 | Q96RI0 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12109832 | 0.78 | ATM (0.41) | F2RL3ALDH1A1CYP3A4TDP1MEN1 | |
| SCHEMBL9305886 | 0.75 | MEN1 (0.38) | F2RL3ALDH1A1CYP3A4TDP1MEN1 | |
| SCHEMBL10448664 | 0.73 | ALDH1A1 (0.60) | F2RL3ALDH1A1CYP3A4TDP1MEN1 | |
| SCHEMBL3923193 | 0.73 | ALDH1A1 (0.47) | F2RL3ALDH1A1CYP3A4TDP1MEN1 | |
| SCHEMBL9305704 | 0.73 | ALDH1A1 (0.37) | F2RL3ALDH1A1CYP3A4TDP1MEN1 | |
| SCHEMBL11709639 | 0.70 | PSMB8 (0.59) | ALDH1A1CYP3A4TDP1MEN1KMT2A | |
| SCHEMBL31293857 | 0.68 | ALDH1A1 (0.33) | F2RL3ALDH1A1CYP3A4TDP1MEN1 | |
| SCHEMBL54176 | 0.68 | PSMB8 (0.36) | F2RL3ALDH1A1CYP3A4TDP1MEN1 | |
| SCHEMBL11781953 | 0.66 | TLR8 (0.43) | ALDH1A1MAPTHPGD | |
| SCHEMBL10759192 | 0.65 | MAPT (0.36) | ALDH1A1MEN1KMT2AKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000030632-A1 | ARYL AND HETEROARYL COMPOUNDS USEFUL AS FIBROBLAST GROWTH FACTOR ANTAGONISTS | EISAI CO., LTD. (JP) | 2000-06-02 | — | — | WO | claimed |