Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | HTR1B | P28222 | 4/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 10/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 9/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.44 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.43 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HTR1D | P28221 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27613071 | 0.83 | HTR1B (0.47) | CYP1A2CYP2C19KDM4EMEN1KMT2A | |
| SCHEMBL11577421 | 0.82 | KDM4E (0.52) | CYP1A2CYP2C19KDM4EMEN1KMT2A | |
| SCHEMBL1356983 | 0.79 | HTR1B (0.47) | CYP1A2CYP2C19KDM4EMEN1KMT2A | |
| SCHEMBL30942689 | 0.79 | SLC6A4 (0.47) | CYP1A2CYP2C19KDM4EMEN1KMT2A | |
| SCHEMBL4982131 | 0.78 | CYP1A2 (0.56) | CYP1A2CYP2C19KDM4EMEN1KMT2A | |
| SCHEMBL13971022 | 0.78 | KDM4E (0.49) | CYP1A2CYP2C19KDM4EMEN1KMT2A | |
| SCHEMBL10344137 | 0.78 | KDM4E (0.49) | CYP1A2CYP2C19KDM4EMEN1KMT2A | |
| SCHEMBL6831487 | 0.78 | HTR1B (0.50) | CYP1A2CYP2C19KDM4EMEN1KMT2A | |
| SCHEMBL5072033 | 0.78 | SLC6A2 (0.53) | CYP1A2CYP2C19KDM4EMEN1KMT2A | |
| SCHEMBL9329809 | 0.77 | CYP1A2 (0.49) | CYP1A2CYP2C19KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0973714-A2 | PRODUCTION OF RACEMIC 2-(6-METHOXY-2-NAPHTHYL)PROPIONIC ACID OR PRECURSORS THEREOF | ALBEMARLE CORPORATION (US) | 2000-01-26 | — | — | EP | disclosed |
| EP-0937021-A1 | PRODUCTION OF NABUMETONE OR PRECURSORS THEREOF | ALBEMARLE CORPORATION (US) | 1999-08-25 | — | — | EP | disclosed |
| US-5907069-A | METHYLATION OF 6-BROMO-2-NAPHTHOL WITH METHYL BROMIDE OR METHYL CHLORIDE AND RECOVERING NABUMETONE | ALBEMARLE CORPORATION (US) | 1999-05-25 | — | — | US | disclosed |
| US-5840996-A | Production of brominated methoxynaphthalene compounds | ALBEMARLE CORPORATION (US) | 1998-11-24 | — | — | US | disclosed |
| WO-1998050334-A1 | PRODUCTION OF BROMINATED METHOXYNAPHTHALENE COMPOUNDS | ALBEMARLE CORPORATION (US) | 1998-11-12 | — | — | WO | disclosed |
| US-5792886-A | METHYLATION OF 6-BROMO-2-NAPHTHOL WITH METHYL BROMIDE TO 2-BROMO-6-METHOXYNAPHTHALENE; FORMING GRIGNARD; REACTING WITH A LOWER ALKYL 2-BROMOPROPIONATE | ALBEMARLE CORPORATION (US) | 1998-08-11 | — | — | US | disclosed |
| WO-1998030528-A2 | PRODUCTION OF RACEMIC 2-(6-METHOXY-2-NAPHTHYL)PROPIONIC ACID OR PRECURSORS THEREOF | ALBEMARLE CORPORATION (US) | 1998-07-16 | — | — | WO | disclosed |
| US-5756851-A | Production of nabumetone or precursors thereof | ALBEMARLE CORPORATION (US) | 1998-05-26 | — | — | US | disclosed |
| WO-1998017616-A1 | PRODUCTION OF NABUMETONE OR PRECURSORS THEREOF | ALBEMARLE CORPORATION (US) | 1998-04-30 | — | — | WO | disclosed |