Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL668904 | 1.00 | KMT2A (0.31) | KMT2ALTC4S | |
| SCHEMBL883057 | 1.00 | KMT2A (0.31) | KMT2ALTC4S | |
| Hydrochloric Acid SCHEMBL4601840 | 0.98 | KMT2A (0.30) | KMT2A | |
| SCHEMBL8130074 | 0.85 | KMT2A (0.33) | KMT2A | |
| SCHEMBL8206048 | 0.80 | — | — | |
| SCHEMBL8228972 | 0.79 | — | — | |
| SCHEMBL14202599 | 0.78 | LTC4S (0.30) | LTC4S | |
| SCHEMBL12207984 | 0.77 | CA12 (0.41) | — | |
| SCHEMBL8141091 | 0.77 | — | — | |
| SCHEMBL8272281 | 0.75 | CA1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2265606-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2015-10-21 | — | — | EP | disclosed |
| EP-1910404-B9 | HCV NS3 PROTEASE INHIBITORS | MERCK SHARP & DOHME (US) | 2014-05-21 | — | — | EP | disclosed |
| EP-2340830-A2 | Hepatitis C Virus Inhibitors | Bristol-Myers Squibb Company (US) | 2011-07-06 | — | — | EP | disclosed |
| WO-2009085659-A1 | CRYSTALLINE FORMS OF N-(TERT-BUTOXYCARBONYL)-3-METHYL-L-VALYL-(4R)-4-((7-CHLORO-4-METHOXY-1-ISOQUINOLINYL)OXY)-N-((1R,2S)-1-((CYCLOPROPYLSULFONYL)CARBAMOYL)-2-VINYLCYCLOPROPYL)-L-PROLINAMIDE | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-07-09 | — | — | WO | disclosed |
| WO-2006086381-A2 | HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-08-17 | — | — | WO | disclosed |