Mellitic Acid

Mellitic Acid

SCHEMBL8009331

O=C(O)CC(C(=O)O)C(C(=O)O)C(C(=O)O)C(CC(=O)O)C(=O)O.O=C(O)c1c(C(=O)O)c(C(=O)O)c(C(=O)O)c(C(=O)O)c1C(=O)O

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.37
FOLH1 Q04609 3/20 0.37
SLC22A6 Q4U2R8 1/20 0.35
CPA1 P15085 2/20 0.31
CPB1 P15086 1/20 0.31
CPA3 P15088 1/20 0.31
CPB2 Q96IY4 1/20 0.31
TET2 Q6N021 3/20 0.30
GABRR1 P24046 2/20 0.30
KDM4A O75164 2/20 0.30
KDM4C Q9H3R0 2/20 0.30
KDM2A Q9Y2K7 2/20 0.30
TET3 O43151 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL786389 0.88 TDP1 (0.72) TDP1SMN1; SMN2FOLH1SLC22A6CPA1
SCHEMBL25414620 0.85 TDP1 (0.68) TDP1SMN1; SMN2FOLH1SLC22A6CPA1
SCHEMBL3285462 0.83 TDP1 (0.72) TDP1SMN1; SMN2FOLH1SLC22A6CPA1
SCHEMBL9355977 0.77 TDP1 (0.93) TDP1SMN1; SMN2FOLH1SLC22A6CPA1
SCHEMBL28060338 0.76 TDP1 (0.62) TDP1SMN1; SMN2FOLH1SLC22A6TET2
SCHEMBL6631810 0.76 TDP1 (0.54) TDP1SMN1; SMN2FOLH1SLC22A6
SCHEMBL16925719 0.74 TDP1 (1.00) TDP1SMN1; SMN2FOLH1SLC22A6CPA1
SCHEMBL22151 0.74 TDP1 (1.00) TDP1SMN1; SMN2FOLH1SLC22A6CPA1
SCHEMBL17517216 0.74 TDP1 (1.00) TDP1SMN1; SMN2FOLH1SLC22A6CPA1
SCHEMBL165643 0.74 TDP1 (1.00) TDP1SMN1; SMN2FOLH1SLC22A6CPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2000034430-A1 DETERGENT BAR COMPOSITION UNILEVER N.V. (NL) 2000-06-15 WO disclosed
EP-0028432-B1 GRANULAR LAUNDRY COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1984-01-18 EP disclosed
US-4321157-A SILICA OR SILICATE, ORGANIC PEROXY ACID BLEACH PRECURSOR, ALIPHATIC ALCOHOL-ALKYLENE OXIDE CONDENSATE NONIONIC SURFACTANT THE PROCTER & GAMBLE COMPANY (US) 1982-03-23 US disclosed