Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.45 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | SLC25A1 | P53007 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1471928 | 0.87 | CYP2C9 (0.49) | THRAMEN1KMT2ACYP2C9CRHBP | |
| SCHEMBL1471717 | 0.87 | MEN1 (0.53) | THRAMEN1KMT2ACYP2C9CRHBP | |
| SCHEMBL1471490 | 0.86 | CYP2C9 (0.51) | THRAMEN1KMT2ACYP2C9CRHBP | |
| SCHEMBL1472067 | 0.85 | CYP2C9 (0.52) | THRAMEN1KMT2ACYP2C9CRHBP | |
| SCHEMBL1472107 | 0.85 | CYP2C9 (0.49) | THRAMEN1KMT2ACYP2C9CRHBP | |
| SCHEMBL1471441 | 0.84 | CRHBP (0.49) | THRAMEN1KMT2ACYP2C9CRHBP | |
| SCHEMBL1472466 | 0.84 | MEN1 (0.57) | THRAMEN1KMT2ACYP2C9GAA | |
| SCHEMBL1471875 | 0.83 | MEN1 (0.57) | THRAMEN1KMT2ACYP2C9GAA | |
| SCHEMBL8009551 | 0.83 | MEN1 (0.53) | THRAMEN1KMT2ACYP2C9CRHBP | |
| SCHEMBL1472009 | 0.83 | TRPV1 (0.50) | THRAMEN1KMT2ACYP2C9CRHBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000035904-A1 | INHIBITORS OF β-LACTAMASES AND USES THEREFOR | NORTHWESTERN UNIVERSITY (US) | 2000-06-22 | — | — | WO | disclosed |