Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 2/20 | 0.61 |
| ▸ | CTSL | P07711 | 8/20 | 0.56 |
| ▸ | CTSB | P07858 | 5/20 | 0.56 |
| ▸ | CTSK | P43235 | 5/20 | 0.55 |
| ▸ | ACE | P12821 | 1/20 | 0.53 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.53 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.53 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.53 |
| ▸ | CTSS | P25774 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7313698 | 0.96 | CAPN1 (0.65) | CAPN1CTSLCTSBCTSKPSMB1 | |
| SCHEMBL14148469 | 0.91 | CAPN1 (0.72) | CAPN1CTSLCTSBCTSKACE | |
| SCHEMBL6276287 | 0.91 | CAPN1 (0.72) | CAPN1CTSLCTSBCTSKACE | |
| SCHEMBL6482122 | 0.91 | CAPN1 (0.72) | CAPN1CTSLCTSBCTSKACE | |
| SCHEMBL29577873 | 0.87 | CAPN1 (0.60) | CAPN1CTSLCTSBCTSKCTSS | |
| SCHEMBL2478311 | 0.87 | CAPN1 (0.67) | CAPN1CTSLCTSBCTSKACE | |
| SCHEMBL8584687 | 0.87 | CAPN1 (0.67) | CAPN1CTSLCTSBCTSKACE | |
| SCHEMBL931659 | 0.86 | CAPN1 (0.69) | CAPN1CTSLCTSBCTSKACE | |
| SCHEMBL7327426 | 0.86 | CAPN1 (0.78) | CAPN1CTSLCTSBCTSKCTSS | |
| SCHEMBL27809377 | 0.86 | CAPN1 (0.78) | CAPN1CTSLCTSBCTSKCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000033654-A1 | USE OF PROTEASE INHIBITORS TO MODULATE CELLULAR PATHWAYS, IMMUNITY AND THERAPIES ASSOCIATED THEREWITH | UNIVERSITY OF MARYLAND BIOTECHNOLOGY INSTITUTE (US) | 2000-06-15 | — | — | WO | disclosed |