SCHEMBL29577873

SCHEMBL29577873

CC(C)C[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)C=[N+]=[N-]

nearest known ligand 0.60

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ CAPN1 P07384 2/20 0.60
▸ CTSK P43235 8/20 0.57
▸ CTSL P07711 8/20 0.56
▸ CTSB P07858 4/20 0.55
▸ CTSS P25774 3/20 0.54
▸ HTRA1 Q92743 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7342916 0.91 CTSK (0.65) CAPN1CTSKCTSLCTSBCTSS
SCHEMBL29358994 0.88 CAPN1 (0.64) CAPN1CTSKCTSLCTSBCTSS
SCHEMBL6272059 0.88 TACR1 (0.59) CTSKCTSLCTSBCTSS
SCHEMBL2601895 0.88 TACR1 (0.59) CTSKCTSLCTSBCTSS
SCHEMBL6272041 0.87 CTSL (0.55) CAPN1CTSKCTSLCTSBCTSS
SCHEMBL5805898 0.87 CAPN1 (0.63) CAPN1CTSKCTSLCTSBCTSS
SCHEMBL8009845 0.87 CAPN1 (0.61) CAPN1CTSKCTSLCTSBCTSS
SCHEMBL14148469 0.86 CAPN1 (0.72) CAPN1CTSKCTSLCTSBCTSS
SCHEMBL6276287 0.86 CAPN1 (0.72) CAPN1CTSKCTSLCTSBCTSS
SCHEMBL6482122 0.86 CAPN1 (0.72) CAPN1CTSKCTSLCTSBCTSS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230142126-A1 METHODS AND COMPOSITIONS FOR THE TREATMENT OF VIRAL DISEASES HEALION BIO., INC. (US) 2023-05-11 — — US claimed
EP-4149552-A1 COMPOSITIONS AND METHODS FOR INCREASING EFFICACY OF A DRUG Healion Bio, Inc. (US) 2023-03-22 — — EP claimed
US-20240000949-A1 Nucleic Acid-Derivatized Therapeutics UNIV CHICAGO (US) 2024-01-04 — — US disclosed
CN-116367849-A Therapeutic agent derived from nucleic acid 芝加哥大学 2023-06-30 — — CN disclosed
US-20230142126-A1 METHODS AND COMPOSITIONS FOR THE TREATMENT OF VIRAL DISEASES HEALION BIO., INC. (US) 2023-05-11 — — US disclosed
EP-4149552-A1 COMPOSITIONS AND METHODS FOR INCREASING EFFICACY OF A DRUG Healion Bio, Inc. (US) 2023-03-22 — — EP disclosed
WO-2022072504-A1 METHODS AND COMPOSITIONS FOR THE TREATMENT OF VIRAL DISEASES HEALION BIO, INC. (US) 2022-04-07 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230142126-A1 METHODS AND COMPOSITIONS FOR THE TREATMENT OF VIRAL DISEASES CTSV, CTSB, CTSS CAPN1 226/4885CTSK 11/4885CTSL 13/4885
US-20240000949-A1 Nucleic Acid-Derivatized Therapeutics NSUN2, NSUN3, POLRMT CAPN1 632/4885CTSK 679/4885CTSL 370/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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