SCHEMBL8009853

SCHEMBL8009853

Fc1c(F)c(F)c(-c2c(F)c(F)c(F)c(F)c2Cl)c(F)c1F

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.32
CES1 P23141 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8010025 0.89 CES2 (0.33) CES2CES1
SCHEMBL15758076 0.86 CES2 (0.32) CES2CES1
SCHEMBL20885106 0.85
SCHEMBL1756501 0.76 CES2 (0.38) CES2CES1
SCHEMBL219009 0.76 CES2 (0.38) CES2CES1
SCHEMBL7214722 0.76 CES2 (0.38) CES2CES1
SCHEMBL14157195 0.76
SCHEMBL7174935 0.76
SCHEMBL14157108 0.76
SCHEMBL29575588 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6129863-A Clean generation of a perfluoroaryl grignard reagent ALBEMARLE CORPORATION (US) 2000-10-10 US disclosed
WO-2000035923-A1 CLEAN GENERATION OF A PERFLUOROARYL GRIGNARD REAGENT ALBEMARLE CORPORATION (US) 2000-06-22 WO disclosed