Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL722321 | 0.79 | MMP8 (0.43) | MMP8PIN1ALDH1A1TRPA1KDM4E | |
| SCHEMBL6067646 | 0.78 | MMP8 (0.43) | MMP8ALDH1A1KDM4EPKMMEN1 | |
| SCHEMBL4314357 | 0.78 | MMP8 (0.43) | MMP8ALDH1A1KDM4EPKMMEN1 | |
| SCHEMBL8013777 | 0.77 | MMP8 (0.39) | MMP8PIN1POLBALDH1A1KDM4E | |
| SCHEMBL8007720 | 0.77 | MMP8 (0.39) | MMP8PIN1POLBALDH1A1KDM4E | |
| SCHEMBL8013697 | 0.77 | MMP8 (0.39) | MMP8PIN1POLBALDH1A1KDM4E | |
| SCHEMBL23906718 | 0.76 | MMP8 (0.41) | MMP8PIN1POLBALDH1A1KDM4E | |
| SCHEMBL16867316 | 0.74 | MMP8 (0.40) | MMP8POLBALDH1A1KDM4EPKM | |
| SCHEMBL7640868 | 0.73 | MMP8 (0.36) | MMP8PIN1POLBALDH1A1KDM4E | |
| SCHEMBL8007259 | 0.73 | MMP8 (0.36) | MMP8PIN1POLBALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000024358-A2 | SYNTHESIS AND USES OF THIOPENTONE ENANTIOMERS | THE UNIVERSITY OF SYDNEY (AU) | 2000-05-04 | — | — | WO | disclosed |