Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.46 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL721987 | 0.94 | MEN1 (0.46) | MEN1KMT2AMAPTATML3MBTL1 | |
| SCHEMBL10926955 | 0.91 | MEN1 (0.46) | MEN1KMT2AMAPTATML3MBTL1 | |
| SCHEMBL16860587 | 0.82 | MEN1 (0.56) | MEN1KMT2AMAPTATML3MBTL1 | |
| SCHEMBL11543099 | 0.81 | MAPT (0.47) | MEN1KMT2AMAPTATML3MBTL1 | |
| SCHEMBL7514889 | 0.79 | MEN1 (0.56) | MEN1KMT2AMAPTATML3MBTL1 | |
| SCHEMBL11070887 | 0.79 | MEN1 (0.56) | MEN1KMT2AMAPTATML3MBTL1 | |
| SCHEMBL11543425 | 0.78 | KMT2A (0.42) | MEN1KMT2AMAPTATML3MBTL1 | |
| SCHEMBL183166 | 0.78 | MEN1 (0.59) | MEN1KMT2AMAPTATML3MBTL1 | |
| SCHEMBL7506698 | 0.78 | MEN1 (0.54) | MEN1KMT2AMAPTATML3MBTL1 | |
| SCHEMBL10871818 | 0.78 | CYP4F2 (0.61) | MEN1KMT2AMAPTATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000024358-A2 | SYNTHESIS AND USES OF THIOPENTONE ENANTIOMERS | THE UNIVERSITY OF SYDNEY (AU) | 2000-05-04 | — | — | WO | disclosed |