SCHEMBL721987

SCHEMBL721987

CCCCC(Br)(C(=O)OCC)C(=O)OCC

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
MAPT P10636 1/20 0.46
ATM Q13315 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
CYP4F2 P78329 2/20 0.43
CYP4A11 Q02928 2/20 0.43
PKM P14618 2/20 0.43
THRB P10828 1/20 0.43
HTT P42858 1/20 0.42
ALDH1A1 P00352 6/20 0.38
KDM4E B2RXH2 2/20 0.37
PIN1 Q13526 1/20 0.37
TRPA1 O75762 1/20 0.37
LMNA P02545 2/20 0.36
CYP1A2 P05177 2/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8009858 0.94 MEN1 (0.53) MEN1KMT2AMAPTATML3MBTL1
SCHEMBL10926955 0.86 MEN1 (0.46) MEN1KMT2AMAPTATML3MBTL1
SCHEMBL11543099 0.82 MAPT (0.47) MEN1KMT2AMAPTATML3MBTL1
SCHEMBL15878899 0.81 AR (0.39) MEN1KMT2AMAPTATML3MBTL1
SCHEMBL18703025 0.80 MEN1 (0.44) MEN1KMT2AMAPTATML3MBTL1
SCHEMBL11543425 0.80 KMT2A (0.42) MEN1KMT2AMAPTATML3MBTL1
SCHEMBL723018 0.78 MEN1 (0.57) MEN1KMT2AMAPTATML3MBTL1
SCHEMBL7531627 0.78 MEN1 (0.45) MEN1KMT2ACYP4F2CYP4A11PKM
SCHEMBL9719079 0.78 MEN1 (0.45) MEN1KMT2ACYP4F2CYP4A11PKM
SCHEMBL7941258 0.77 CYP4F2 (0.69) MEN1KMT2AMAPTATML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10364304-B2 Method for producing solid catalyst component for olefin polymerization, catalyst for olefin polymerization, and method for producing olefin polymer TOHO TITANIUM CO., LTD. (JP) 2019-07-30 US disclosed
EP-1533322-B1 SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND CATALYST TOHO TITANIUM CO LTD (JP) 2019-05-01 EP disclosed
EP-2730590-B1 SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, CATALYST FOR OLEFIN POLYMERIZATION, AND METHOD FOR PRODUCING OLEFIN POLYMER TOHO TITANIUM CO LTD (JP) 2018-04-04 EP disclosed
US-20150368281-A1 Platinum Compounds Of Malonic Acid Derivative Having Leaving Group Containing Amino Or Alkylamino BEIJING FSWELCOME TECHNOLOGY DEVELOPMENT CO., LTD (CN) 2015-12-24 US disclosed
US-9206265-B2 Solid catalyst component for olefin polymerization, catalyst for olefin polymerization, and method for producing olefin polymer TOHO TITANIUM CO., LTD. (JP) 2015-12-08 US disclosed
EP-2924044-A1 PLATINUM COMPOUND OF MALONIC ACID DERIVATIVE HAVING LEAVING GROUP CONTAINING AMINO OR ALKYLAMINO BEIJING FSWELCOME TECHNOLOGY DEVELOPMENT, CO., LTD (CN) 2015-09-30 EP disclosed
EP-2374821-B1 MANUFACTURING METHOD OF SOLID CATALYST COMPONENT AND OF CATALYST FOR OLEFIN POLYMERIZATION TOHO TITANIUM CO LTD (JP) 2015-05-06 EP disclosed
US-20140221583-A1 SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, CATALYST FOR OLEFIN POLYMERIZATION, AND METHOD FOR PRODUCING OLEFIN POLYMER TOHO TITANIUM CO., LTD. (JP) 2014-08-07 US disclosed
US-20140206827-A1 METHOD FOR PRODUCING SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, CATALYST FOR OLEFIN POLYMERIZATION, AND METHOD FOR PRODUCING OLEFIN POLYMER TOHO TITANIUM CO., LTD. (JP) 2014-07-24 US disclosed
EP-2730590-A1 SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, CATALYST FOR OLEFIN POLYMERIZATION, AND METHOD FOR PRODUCING OLEFIN POLYMER Toho Titanium CO., LTD. (JP) 2014-05-14 EP disclosed
EP-1829898-A1 SOLID CATALYST COMPONENT AND CATALYST FOR POLYMERIZATION OF OLEFIN, AND METHOD FOR PRODUCING POLYMER OR COPOLYMER OF OLEFIN USING THE SAME Toho Catalyst Co., Ltd. (JP) 2007-09-05 EP disclosed
EP-1790667-A1 CATALYST FOR POLYMERIZATION OF OLEFINS AND METHOD FOR POLYMERIZATION OF OLEFINS Toho Catalyst Co., Ltd. (JP) 2007-05-30 EP disclosed
US-7208435-B2 Solid catalyst component for olefin polymerization and catalyst TOHO CATALYST CO., LTD. (JP) 2007-04-24 US disclosed
EP-1202974-B1 PYRIMIDINE-2,4,6-TRIONE METALLOPROTEINASE INHIBITORS PFIZER PROD INC (US) 2005-11-09 EP disclosed
US-20050227856-A1 Solid catalyst component for olefin polymerization and catalyst TOHO CATALYST CO., LTD. (JP) 2005-10-13 US disclosed
EP-1533322-A1 SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND CATALYST Toho Catalyst Co., Ltd. (JP) 2005-05-25 EP disclosed
US-6579982-B1 Treating inflammation, cancer PFIZER INC. 2003-06-17 US disclosed
EP-1202974-A1 PYRIMIDINE-2,4,6-TRIONE METALLOPROTEINASE INHIBITORS Pfizer Products Inc. (US) 2002-05-08 EP disclosed
WO-2001012611-A1 PYRIMIDINE-2,4,6-TRIONE METALLOPROTEINASE INHIBITORS PFIZER PRODUCTS INC. (US) 2001-02-22 WO disclosed
US-4077982-A HERBICIDES FMC CORPORATION (US) 1978-03-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150368281-A1 Platinum Compounds Of Malonic Acid Derivative Having Leaving Group Containing Amino Or Alkylamino SLC7A1, ME3, SLC7A5 MEN1 669/4885KMT2A 1844/4885MAPT 3319/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.