Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | TSPO | P30536 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | RGS12 | O14924 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32661890 | 0.80 | MAPT (0.39) | CA12CA1CA2CA9TSPO | |
| SCHEMBL28741574 | 0.80 | GRIA1 (0.48) | HSD17B10CYP3A4SLC7A5USP2HIF1A | |
| Hydrochloric Acid SCHEMBL31407596 | 0.79 | MAPT (0.39) | CA12CA1CA2CA9TSPO | |
| SCHEMBL2263341 | 0.78 | HSD17B10 (0.49) | HSD17B10CYP3A4SLC7A5USP2HIF1A | |
| SCHEMBL155235 | 0.78 | NOS3 (0.55) | SLC7A5HIF1AKDM4EMEN1LMNA | |
| SCHEMBL155234 | 0.78 | NOS3 (0.55) | SLC7A5HIF1AKDM4EMEN1LMNA | |
| SCHEMBL4595466 | 0.78 | NOS3 (0.55) | SLC7A5HIF1AKDM4EMEN1LMNA | |
| SCHEMBL29750308 | 0.78 | NOS3 (0.55) | SLC7A5HIF1AKDM4EMEN1LMNA | |
| SCHEMBL13957557 | 0.77 | GRIA1 (0.48) | HSD17B10CYP3A4SLC7A5USP2HIF1A | |
| SCHEMBL30759485 | 0.77 | HSD17B10 (0.47) | HSD17B10CYP3A4SLC7A5USP2HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0850316-A4 | CRYPTOPHYCINS FROM ABERRANT BIOSYNTHESIS | UNIV HAWAII (US) | 2000-08-23 | — | — | EP | disclosed |
| EP-0850316-A1 | CRYPTOPHYCINS FROM ABERRANT BIOSYNTHESIS | UNIVERSITY OF HAWAII (US) | 1998-07-01 | — | — | EP | disclosed |
| WO-1997008334-A1 | CRYPTOPHYCINS FROM ABERRANT BIOSYNTHESIS | UNIVERSITY OF HAWAII (US) | 1997-03-06 | — | — | WO | disclosed |