Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | GRN | P28799 | 3/20 | 0.43 |
| ▸ | SORT1 | Q99523 | 3/20 | 0.43 |
| ▸ | GCGR | P47871 | 2/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | BCR | P11274 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GUCY1B2 | O75343 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8009943 | 0.91 | ALDH1A1 (0.47) | ALDH1A1GAARECQLGRNSORT1 | |
| SCHEMBL8010513 | 0.87 | GRN (0.44) | ALDH1A1GRNSORT1SLC6A2SLC6A4 | |
| SCHEMBL8008243 | 0.85 | GRN (0.44) | ALDH1A1GRNSORT1SLC6A2SLC6A4 | |
| SCHEMBL7999906 | 0.84 | GRN (0.55) | ALDH1A1GRNSORT1SLC6A2SLC6A4 | |
| SCHEMBL8009940 | 0.84 | ALDH1A1 (0.57) | ALDH1A1GAARECQLSMN1; SMN2TP53 | |
| SCHEMBL7999008 | 0.83 | KDM4E (0.44) | GRNSORT1SLC6A2SLC6A4SMN1; SMN2 | |
| SCHEMBL8009903 | 0.82 | KDM4E (0.45) | GAAGRNSORT1SLC6A2SLC6A4 | |
| SCHEMBL5038706 | 0.82 | KDM4E (0.51) | ALDH1A1GRNSORT1SLC6A2SLC6A4 | |
| SCHEMBL8007915 | 0.81 | KDM4E (0.45) | ALDH1A1GRNSORT1SLC6A2SLC6A4 | |
| 3,4,5-Trimethoxybenzamide SCHEMBL8009946 | 0.81 | GRN (0.42) | GAAGRNSORT1SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000027394-A1 | ACTIVATORS OF SOLUBLE GUANYLATE CYCLASE | UNIVERSITY COLLEGE LONDON (GB) | 2000-05-18 | — | — | WO | claimed |
| WO-2000027394-A1 | ACTIVATORS OF SOLUBLE GUANYLATE CYCLASE | UNIVERSITY COLLEGE LONDON (GB) | 2000-05-18 | — | — | WO | disclosed |