Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 14/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 14/20 | 0.55 |
| ▸ | MAPT | P10636 | 11/20 | 0.55 |
| ▸ | USP2 | O75604 | 4/20 | 0.55 |
| ▸ | CRHBP | P24387 | 2/20 | 0.55 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.55 |
| ▸ | IDE | P14735 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.54 |
| ▸ | THRB | P10828 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 7/20 | 0.53 |
| ▸ | NPC1 | O15118 | 6/20 | 0.53 |
| ▸ | HTT | P42858 | 5/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | BLM | P54132 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8009973 | 0.82 | MEN1 (0.56) | MEN1KMT2AMAPTUSP2CRHBP | |
| SCHEMBL13222293 | 0.80 | MEN1 (0.58) | MEN1KMT2AMAPTUSP2CRHBP | |
| SCHEMBL18103637 | 0.76 | MAPT (0.63) | MEN1KMT2AMAPTUSP2CRHBP | |
| SCHEMBL13243162 | 0.75 | MEN1 (0.59) | MEN1KMT2AMAPTUSP2CRHBP | |
| SCHEMBL10036072 | 0.75 | MAPT (0.60) | MEN1KMT2AMAPTUSP2CRHBP | |
| SCHEMBL13709032 | 0.75 | MEN1 (0.69) | MEN1KMT2AMAPTUSP2CRHBP | |
| SCHEMBL10331919 | 0.75 | MEN1 (0.79) | MEN1KMT2AMAPTUSP2CRHBP | |
| SCHEMBL14301214 | 0.75 | MEN1 (0.79) | MEN1KMT2AMAPTUSP2CRHBP | |
| SCHEMBL8011177 | 0.74 | MEN1 (0.58) | MEN1KMT2AMAPTUSP2CRHBP | |
| SCHEMBL8011171 | 0.74 | MEN1 (0.58) | MEN1KMT2AMAPTUSP2CRHBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000054771-A1 | THE USE OF 3,5-PYRAZOLIDINEDIONE DERIVATIVES TO COMBAT VIRAL INFECTIONS | NORMEDICA AS (NO) | 2000-09-21 | — | — | WO | claimed |
| WO-2000054771-A1 | THE USE OF 3,5-PYRAZOLIDINEDIONE DERIVATIVES TO COMBAT VIRAL INFECTIONS | NORMEDICA AS (NO) | 2000-09-21 | — | — | WO | disclosed |