Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 16/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 16/20 | 0.58 |
| ▸ | MAPT | P10636 | 13/20 | 0.58 |
| ▸ | USP2 | O75604 | 5/20 | 0.58 |
| ▸ | CRHBP | P24387 | 3/20 | 0.58 |
| ▸ | CRHR2 | Q13324 | 3/20 | 0.58 |
| ▸ | IDE | P14735 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 7/20 | 0.55 |
| ▸ | BLM | P54132 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 10/20 | 0.54 |
| ▸ | NPC1 | O15118 | 8/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | POLB | P06746 | 4/20 | 0.54 |
| ▸ | THRB | P10828 | 3/20 | 0.54 |
| ▸ | RECQL | P46063 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8011171 | 1.00 | MEN1 (0.58) | MEN1KMT2AMAPTUSP2CRHBP | |
| SCHEMBL8011193 | 0.89 | PDF (0.54) | MEN1KMT2AMAPTUSP2CRHBP | |
| SCHEMBL8011192 | 0.89 | PDF (0.54) | MEN1KMT2AMAPTUSP2CRHBP | |
| SCHEMBL2560687 | 0.84 | MEN1 (0.60) | MEN1KMT2AMAPTUSP2CRHBP | |
| SCHEMBL2560692 | 0.84 | MEN1 (0.60) | MEN1KMT2AMAPTUSP2CRHBP | |
| SCHEMBL2560695 | 0.84 | MEN1 (0.60) | MEN1KMT2AMAPTUSP2CRHBP | |
| SCHEMBL13243162 | 0.84 | MEN1 (0.59) | MEN1KMT2AMAPTUSP2CRHBP | |
| SCHEMBL9785932 | 0.83 | MEN1 (0.59) | MEN1KMT2AMAPTUSP2CRHBP | |
| SCHEMBL9785928 | 0.83 | MEN1 (0.59) | MEN1KMT2AMAPTUSP2CRHBP | |
| SCHEMBL10578211 | 0.80 | MEN1 (0.65) | MEN1KMT2AMAPTUSP2CRHBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000030632-A1 | ARYL AND HETEROARYL COMPOUNDS USEFUL AS FIBROBLAST GROWTH FACTOR ANTAGONISTS | EISAI CO., LTD. (JP) | 2000-06-02 | — | — | WO | claimed |
| WO-2000030632-A1 | ARYL AND HETEROARYL COMPOUNDS USEFUL AS FIBROBLAST GROWTH FACTOR ANTAGONISTS | EISAI CO., LTD. (JP) | 2000-06-02 | — | — | WO | disclosed |