Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | SLC22A16 | Q86VW1 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.33 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2337444 | 0.97 | ALDH1A1 (0.56) | ALDH1A1TDP1SLC22A6TRPA1SLC22A16 | |
| SCHEMBL2592557 | 0.85 | SLC22A6 (0.72) | ALDH1A1TDP1SLC22A6MAPTLMNA | |
| SCHEMBL9782340 | 0.85 | SLC22A6 (0.72) | ALDH1A1TDP1SLC22A6MAPTLMNA | |
| SCHEMBL15135014 | 0.83 | ALDH1A1 (0.43) | ALDH1A1TDP1SLC22A6TRPA1SLC22A16 | |
| SCHEMBL15135051 | 0.83 | ALDH1A1 (0.43) | ALDH1A1TDP1SLC22A6TRPA1SLC22A16 | |
| SCHEMBL12341066 | 0.81 | — | — | |
| SCHEMBL638400 | 0.81 | — | — | |
| SCHEMBL689567 | 0.81 | — | — | |
| SCHEMBL14706003 | 0.81 | — | — | |
| SCHEMBL12835746 | 0.81 | ALDH1A1 (0.48) | ALDH1A1TDP1SLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6162912-A | Process of preparing tetraacetic acid derivatives | DIBRA S.P.A. (IT) | 2000-12-19 | — | — | US | disclosed |
| US-6048980-A | AMINATION WITH DEHYDROHALOGENATION FOLLOWED BY HYDROLYSIS OF ESTER GROUP | DIBRA S.P.A (IT) | 2000-04-11 | — | — | US | disclosed |
| US-6028194-A | SYNTHESIS OF GADOTERIDOL AND GADOBUTROL CONTRAST AGENTS FOR THE RESONANCE TECHNIQUE (MAGNETIC RESONANCE IMAGING) | DIBRA S.P.A. (IT) | 2000-02-22 | — | — | US | disclosed |
| US-6020485-A | Process for producing tetraazabicyclo monoacetic acid | DIBRA S.P.A. (IT) | 2000-02-01 | — | — | US | disclosed |
| US-5977353-A | 1,4,7,10-tetraazabicyclo[8.2.2]tetradecan-2-one, a process for the preparation thereof and the use thereof for the preparation of tetraazamacrocycles | DIBRA S.P.A. (IT) | 1999-11-02 | — | — | US | disclosed |
| EP-0220118-B1 | BICYCLIC NAPHTHALENIC DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN HUMAN AND VETERINARY MEDICINE AND COSMETICS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA - CIRD GALDERMA (FR) | 1992-01-02 | — | — | EP | disclosed |
| EP-0220118-A2 | Bicyclic naphthalenic derivatives, process for their preparation and their use in human and veterinary medicine and cosmetics | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA - CIRD GALDERMA (FR) | 1987-04-29 | — | — | EP | disclosed |