Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.33 |
| ▸ | SHBG | P04278 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28852334 | 0.94 | TSHR (0.48) | TSHRALDH1A1SIGMAR1PLA2G2CSHBG | |
| SCHEMBL29047311 | 0.94 | TSHR (0.47) | TSHRALDH1A1PLA2G2CSHBG | |
| SCHEMBL17215700 | 0.94 | TSHR (0.42) | TSHRALDH1A1SIGMAR1PLA2G2CSHBG | |
| SCHEMBL29047254 | 0.92 | TSHR (0.48) | TSHRALDH1A1PLA2G2CSHBG | |
| SCHEMBL8011138 | 0.86 | SHBG (0.43) | TSHRSIGMAR1SHBGEPHX1EPHX2 | |
| SCHEMBL11675599 | 0.86 | SHBG (0.43) | TSHRSIGMAR1SHBGEPHX1EPHX2 | |
| SCHEMBL16109513 | 0.86 | SHBG (0.43) | TSHRSIGMAR1SHBGEPHX1EPHX2 | |
| SCHEMBL27829867 | 0.86 | SHBG (0.43) | TSHRSIGMAR1SHBGEPHX1EPHX2 | |
| SCHEMBL314955 | 0.86 | SHBG (0.43) | TSHRSIGMAR1SHBGEPHX1EPHX2 | |
| SCHEMBL27939506 | 0.86 | SHBG (0.43) | TSHRSIGMAR1SHBGEPHX1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6105691-A | CONTAINING CAUSTIC, A NATURAL WAX, A NATURAL THINNER, GLYCEROL, PHOSPHORIC ACID AND/OR BORIC ACID FOR INCREASING DRILLING LUBRICATION, THINNING THE DRILLING MUD, DECREASING BIT BALLING AND ROCK RESISTANCE | SPECTRAL, INC. (US) | 2000-08-22 | — | — | US | disclosed |