SCHEMBL8010104

SCHEMBL8010104

O=C(O)C12CCCC1C1C=CC2C1

nearest known ligand 0.31

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.31
TDP1 Q9NUW8 2/20 0.31
APEX1 P27695 1/20 0.31
MEN1 O00255 1/20 0.30
ALDH1A1 P00352 1/20 0.30
KMT2A Q03164 1/20 0.30
CTDSP1 Q9GZU7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22115477 0.80
SCHEMBL5862132 0.67
SCHEMBL10388136 0.67 KDM4E (0.34)
SCHEMBL19003826 0.66 CYP1A2 (0.36)
SCHEMBL22115474 0.66 POLB (0.32) POLBTDP1APEX1
SCHEMBL22115472 0.66 POLB (0.32) POLBTDP1APEX1
SCHEMBL22115475 0.66 POLB (0.32) POLBTDP1APEX1
SCHEMBL2325064 0.64 SLC1A2 (0.33)
SCHEMBL1626704 0.64 SLC1A2 (0.33)
SCHEMBL11877415 0.64 SLC1A2 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0807100-B1 TRICYCLOCARBOXYLATE, METHOD FOR PREPARING THE SAME AND PERFUME COMPRISING THE SAME KAO CORP (JP) 2000-01-26 EP claimed
EP-0807100-A1 TRICYCLOCARBOXYLATE, METHOD FOR PREPARING THE SAME AND PERFUME COMPRISING THE SAME Kao Corporation (JP) 1997-11-19 EP claimed
WO-1997019906-A1 TRICYCLOCARBOXYLATE, METHOD FOR PREPARING THE SAME AND PERFUME COMPRISING THE SAME KAO CORPORATION (JP) 1997-06-05 WO claimed
CN-1071737-C Process for preparing tricyclic carboxylic acid esters KAO CORP (JP) 2001-09-26 CN disclosed
EP-0807100-B1 TRICYCLOCARBOXYLATE, METHOD FOR PREPARING THE SAME AND PERFUME COMPRISING THE SAME KAO CORP (JP) 2000-01-26 EP disclosed
EP-0807100-B1 TRICYCLOCARBOXYLATE, METHOD FOR PREPARING THE SAME AND PERFUME COMPRISING THE SAME KAO CORP (JP) 2000-01-26 EP disclosed
CN-1169712-A Tricyclic carboxylic acid ester, process for producing the same, and perfume containing the same KAO CORP (JP) 1998-01-07 CN disclosed
EP-0807100-A1 TRICYCLOCARBOXYLATE, METHOD FOR PREPARING THE SAME AND PERFUME COMPRISING THE SAME Kao Corporation (JP) 1997-11-19 EP disclosed
EP-0807100-A1 TRICYCLOCARBOXYLATE, METHOD FOR PREPARING THE SAME AND PERFUME COMPRISING THE SAME Kao Corporation (JP) 1997-11-19 EP disclosed
WO-1997019906-A1 TRICYCLOCARBOXYLATE, METHOD FOR PREPARING THE SAME AND PERFUME COMPRISING THE SAME KAO CORPORATION (JP) 1997-06-05 WO disclosed
WO-1997019906-A1 TRICYCLOCARBOXYLATE, METHOD FOR PREPARING THE SAME AND PERFUME COMPRISING THE SAME KAO CORPORATION (JP) 1997-06-05 WO disclosed