SCHEMBL10388136

SCHEMBL10388136

O=C(O)C1(C2CC3C=CC2C3)CC2C=CC1C2

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.34
LMNA P02545 1/20 0.34
EPHX2 P34913 1/20 0.31
CYP2D6 P10635 1/20 0.30
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5318552 0.71 CYP2D6 (0.33) EPHX2CYP2D6CYP2C19
SCHEMBL7567525 0.68 P2RX7 (0.35) KDM4ELMNACYP2D6CYP2C19
SCHEMBL7714730 0.68
SCHEMBL10388299 0.68 KDM4E (0.36) KDM4ELMNAEPHX2CYP2D6CYP2C19
SCHEMBL9079943 0.67 CYP2D6 (0.37) CYP2D6CYP2C19
SCHEMBL6429482 0.67 CYP2D6 (0.37) CYP2D6CYP2C19
SCHEMBL7712386 0.67
SCHEMBL8010104 0.67 POLB (0.31)
SCHEMBL10976282 0.67
SCHEMBL8732519 0.66 CYP2D6 (0.36) CYP2D6CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4923943-A DICYCLOPENTADIENE, NORBORNENYL ESTERS OF NORBORNENYL ACIDS HERCULES INCORPORATED (US) 1990-05-08 US claimed
US-4923943-A DICYCLOPENTADIENE, NORBORNENYL ESTERS OF NORBORNENYL ACIDS HERCULES INCORPORATED (US) 1990-05-08 US disclosed