⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL801058 | 1.00 | — | — | |
| SCHEMBL801057 | 1.00 | — | — | |
| SCHEMBL17365011 | 0.81 | — | — | |
| SCHEMBL752269 | 0.76 | — | — | |
| SCHEMBL12869036 | 0.76 | — | — | |
| SCHEMBL12868839 | 0.76 | — | — | |
| SCHEMBL24050764 | 0.75 | TRPA1 (0.31) | — | |
| SCHEMBL10290149 | 0.75 | TRPA1 (0.31) | — | |
| SCHEMBL12868505 | 0.75 | TRPA1 (0.31) | — | |
| SCHEMBL950830 | 0.75 | TRPA1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021237121-A1 | SUBSTITUTED PYRIDINES | GOSSAMER BIO SERVICES, INC. (US) | 2021-11-25 | — | — | WO | disclosed |
| US-8455522-B2 | Benzoxazolone derivatives as aldosterone synthase inhibitors | NOVARTIS AG (CH) | 2013-06-04 | — | — | US | disclosed |
| US-8455522-B2 | Benzoxazolone derivatives as aldosterone synthase inhibitors | NOVARTIS AG (CH) | 2013-06-04 | — | — | US | disclosed |
| US-20120071514-A1 | BENZOXAZOLONE DERIVATIVES AS ALDOSTERONE SYNTHASE INHIBITORS | NOVARTIS AG (CH) | 2012-03-22 | — | — | US | disclosed |