SCHEMBL8010291

SCHEMBL8010291

CC(C)(OC=O)C1CCCCN1

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.33
FDPS P14324 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28231331 0.93 KDM4E (0.34) TDP1
SCHEMBL16297547 0.76 KDM4E (0.31)
Tert-Butyl Formate SCHEMBL27630859 0.74 TDP1 (0.48) TDP1FDPS
Tert-Butyl Formate SCHEMBL28011984 0.71 TDP1 (0.45) TDP1
Tert-Butyl Formate SCHEMBL27711373 0.71 TDP1 (0.45) TDP1
SCHEMBL5142865 0.71 SLC6A3 (0.31) FDPS
SCHEMBL5243050 0.71 KDM4E (0.32) FDPS
SCHEMBL4669976 0.71 TDP1 (0.42) TDP1
SCHEMBL1547510 0.71 CYP2D6 (0.34) FDPS
SCHEMBL3229383 0.71 CYP2D6 (0.34) FDPS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6090808-A PSYCHOLOGICAL DISORDERS; ANTICONVULSANTS H. LUNDBECK A/S (DK) 2000-07-18 US claimed
EP-0649407-B1 DIMERIC PIPERIDINE, TETRAHYDROPYRIDINE AND PIPERAZINE DERIVATIVES LUNDBECK & CO AS H (DK) 1998-08-05 EP claimed
US-6090808-A PSYCHOLOGICAL DISORDERS; ANTICONVULSANTS H. LUNDBECK A/S (DK) 2000-07-18 US disclosed
EP-0649407-B1 DIMERIC PIPERIDINE, TETRAHYDROPYRIDINE AND PIPERAZINE DERIVATIVES LUNDBECK & CO AS H (DK) 1998-08-05 EP disclosed
US-5658921-A POTENT SIGMA RECEPTOR LIGANDS; WATER SOLUBILITY; SYMMETRY H. LUNDBECK A/S (DK) 1997-08-19 US disclosed