Aniline

Aniline

SCHEMBL8010652

Nc1ccccc1.c1ccc(Nc2cccc3ccccc23)cc1

nearest known ligand 0.81

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.81
HPGD P15428 3/20 0.81
ALOX15 P16050 3/20 0.81
CYP3A4 P08684 2/20 0.81
TP53 P04637 2/20 0.81
HSD17B10 Q99714 2/20 0.81
ATM Q13315 2/20 0.81
TSHR P16473 1/20 0.81
CDC25B P30305 1/20 0.81
MAPT P10636 6/20 0.64
KDM4E B2RXH2 6/20 0.64
GAA P10253 6/20 0.64
MEN1 O00255 4/20 0.64
KMT2A Q03164 4/20 0.64
TDP1 Q9NUW8 3/20 0.64
GLA P06280 1/20 0.64
RECQL P46063 1/20 0.64
FADS1 O60427 1/20 0.57
RAB9A P51151 1/20 0.56
LMNA P02545 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzidine SCHEMBL27521713 0.91 ALDH1A1 (0.73) ALDH1A1HPGDALOX15CYP3A4TP53
SCHEMBL29413845 0.91 ALDH1A1 (0.71) ALDH1A1HPGDALOX15CYP3A4TP53
SCHEMBL94482 0.91 ALDH1A1 (0.71) ALDH1A1HPGDALOX15CYP3A4TP53
SCHEMBL29813142 0.91 ALDH1A1 (0.71) ALDH1A1HPGDALOX15CYP3A4TP53
SCHEMBL29350230 0.90 ALDH1A1 (1.00) ALDH1A1HPGDALOX15CYP3A4TP53
SCHEMBL19796 0.90 ALDH1A1 (1.00) ALDH1A1HPGDALOX15CYP3A4TP53
Hydrochloric Acid SCHEMBL7408656 0.88 ALDH1A1 (0.96) ALDH1A1HPGDALOX15CYP3A4TP53
Ammonia Solution, Strong SCHEMBL20918916 0.88 ALDH1A1 (0.96) ALDH1A1HPGDALOX15CYP3A4TP53
Diphenylamine SCHEMBL1072941 0.88 ALDH1A1 (0.96) ALDH1A1HPGDALOX15CYP3A4TP53
SCHEMBL27924058 0.88 ALDH1A1 (0.96) ALDH1A1HPGDALOX15CYP3A4TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0972194-A2 COMPOSITIONS AND METHODS FOR INHIBITING LIGHT-INDUCED INACTIVATION OF BIOLOGICAL REAGENTS BIOSITE DIAGNOSTICS INC. (US) 2000-01-19 EP disclosed
WO-1998045705-A2 COMPOSITIONS AND METHODS FOR INHIBITING LIGHT-INDUCED INACTIVATION OF BIOLOGICAL REAGENTS BIOSITE DIAGNOSTICS INCORPORATED (US) 1998-10-15 WO disclosed