Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 20/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2575755 | 0.89 | P2RX7 (1.00) | P2RX7 | |
| SCHEMBL2575754 | 0.89 | P2RX7 (1.00) | P2RX7 | |
| SCHEMBL2581764 | 0.85 | P2RX7 (1.00) | P2RX7 | |
| SCHEMBL2581765 | 0.85 | P2RX7 (1.00) | P2RX7 | |
| SCHEMBL2578299 | 0.85 | P2RX7 (1.00) | P2RX7 | |
| SCHEMBL2578300 | 0.85 | P2RX7 (1.00) | P2RX7 | |
| SCHEMBL2574323 | 0.85 | P2RX7 (1.00) | P2RX7 | |
| SCHEMBL2574321 | 0.85 | P2RX7 (1.00) | P2RX7 | |
| SCHEMBL2581860 | 0.82 | P2RX7 (1.00) | P2RX7 | |
| SCHEMBL2581865 | 0.82 | P2RX7 (1.00) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009074518-A1 | COMBINATIONS OF PROLINAMIDE P2X7 MODULATORS WITH FURTHER THERAPEUTIC AGENTS | GLAXO GROUP LIMITED (GB) | 2009-06-18 | — | — | WO | disclosed |