Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.35 |
| ▸ | KCNA3 | P22001 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | KDM1A | O60341 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8011521 | 0.94 | KDM4E (0.40) | KDM4EALDH1A1HSD17B10POLBMAPT | |
| SCHEMBL9443604 | 0.85 | KDM1A (0.37) | KDM4EALDH1A1HSD17B10POLBMAPT | |
| SCHEMBL8008403 | 0.84 | KDM1A (0.38) | KDM4EALDH1A1HSD17B10POLBMAPT | |
| SCHEMBL8013923 | 0.81 | MAOB (0.35) | KDM4EALDH1A1HSD17B10POLBMAPT | |
| SCHEMBL17924142 | 0.80 | KDM4E (0.47) | KDM4EALDH1A1HSD17B10POLBMAPT | |
| SCHEMBL8010863 | 0.80 | KDM1A (0.35) | KDM4EALDH1A1HSD17B10POLBMAPT | |
| SCHEMBL8011917 | 0.79 | KDM4E (0.37) | KDM4EALDH1A1HSD17B10POLBMAPT | |
| SCHEMBL3359444 | 0.76 | MAOA (0.41) | KDM4EALDH1A1HSD17B10MAPTSMN1; SMN2 | |
| SCHEMBL3360003 | 0.75 | MAOA (0.41) | KDM4EALDH1A1HSD17B10MAPTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4193524 | 0.75 | MAOA (0.41) | KDM4EALDH1A1HSD17B10MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1044066-A1 | BATCH DEVICES FOR THE REDUCTION OF COMPOUNDS FROM BIOLOGICAL COMPOSITIONS CONTAINING CELLS AND METHODS OF USE | Cerus Corporation (US) | 2000-10-18 | — | — | EP | disclosed |
| WO-1999034914-A1 | BATCH DEVICES FOR THE REDUCTION OF COMPOUNDS FROM BIOLOGICAL COMPOSITIONS CONTAINING CELLS AND METHODS OF USE | CERUS CORPORATION (US) | 1999-07-15 | — | — | WO | disclosed |