Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | DRD4 | P21917 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.33 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.33 |
| ▸ | CTSD | P07339 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.33 |
| ▸ | GCGR | P47871 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8011360 | 1.00 | TSHR (0.38) | TSHRSLC6A4SLC6A3DRD2DRD4 | |
| SCHEMBL8011364 | 1.00 | TSHR (0.38) | TSHRSLC6A4SLC6A3DRD2DRD4 | |
| SCHEMBL7769727 | 0.92 | TSHR (0.36) | TSHRSLC6A4SLC6A3DRD2DRD4 | |
| SCHEMBL8015344 | 0.92 | TSHR (0.36) | TSHRSLC6A4SLC6A3DRD2DRD4 | |
| SCHEMBL7769722 | 0.92 | TSHR (0.36) | TSHRSLC6A4SLC6A3DRD2DRD4 | |
| SCHEMBL8015349 | 0.92 | TSHR (0.36) | TSHRSLC6A4SLC6A3DRD2DRD4 | |
| SCHEMBL7769719 | 0.92 | TSHR (0.36) | TSHRSLC6A4SLC6A3DRD2DRD4 | |
| SCHEMBL8015343 | 0.92 | TSHR (0.36) | TSHRSLC6A4SLC6A3DRD2DRD4 | |
| SCHEMBL8447740 | 0.86 | TSHR (0.43) | TSHRSLC6A4SLC6A3DRD2DRD4 | |
| SCHEMBL4803252 | 0.86 | TSHR (0.43) | TSHRSLC6A4SLC6A3DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0692485-B1 | Cyclohexane carbaldehyde compounds and processes for preparing silacyclohexane-based liquid crystal compounds from the carbaldehyde compound | SHINETSU CHEMICAL CO (JP) | 2000-01-05 | — | — | EP | disclosed |
| EP-0665232-B1 | A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHINETSU CHEMICAL CO (JP) | 1999-12-15 | — | — | EP | disclosed |
| US-5519156-A | Cyclohexane carbaldehyde compounds and processes for preparing silacyclohexane-based liquid crystal compounds from the carbaldehyde | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-05-21 | — | — | US | disclosed |
| US-5498737-A | Silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-03-12 | — | — | US | disclosed |
| EP-0692485-A1 | Cyclohexane carbaldehyde compounds and processes for preparing silacyclohexane-based liquid crystal compounds from the carbaldehyde compound | Shin-Etsu Chemical Co., Ltd. (JP) | 1996-01-17 | — | — | EP | disclosed |
| EP-0665232-A1 | A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | Shin-Etsu Chemical Co., Ltd. (JP) | 1995-08-02 | — | — | EP | disclosed |