Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.34 |
| ▸ | DRD4 | P21917 | 2/20 | 0.34 |
| ▸ | DRD3 | P35462 | 2/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | LIPE | Q05469 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | GCGR | P47871 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8015344 | 1.00 | TSHR (0.36) | TSHRSLC6A4SLC6A3DRD2DRD4 | |
| SCHEMBL8015349 | 1.00 | TSHR (0.36) | TSHRSLC6A4SLC6A3DRD2DRD4 | |
| SCHEMBL7762574 | 0.94 | FAAH (0.35) | TSHRSLC6A4SLC6A3ALOX5PPARG | |
| SCHEMBL7762577 | 0.94 | FAAH (0.35) | TSHRSLC6A4SLC6A3ALOX5PPARG | |
| SCHEMBL7762581 | 0.94 | FAAH (0.35) | TSHRSLC6A4SLC6A3ALOX5PPARG | |
| SCHEMBL8043879 | 0.93 | TSHR (0.39) | TSHRSLC6A4SLC6A3DRD2DRD4 | |
| SCHEMBL8043882 | 0.93 | TSHR (0.39) | TSHRSLC6A4SLC6A3DRD2DRD4 | |
| SCHEMBL8011364 | 0.92 | TSHR (0.38) | TSHRSLC6A4SLC6A3DRD2DRD4 | |
| SCHEMBL8011361 | 0.92 | TSHR (0.38) | TSHRSLC6A4SLC6A3DRD2DRD4 | |
| SCHEMBL8011360 | 0.92 | TSHR (0.38) | TSHRSLC6A4SLC6A3DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0692485-B1 | Cyclohexane carbaldehyde compounds and processes for preparing silacyclohexane-based liquid crystal compounds from the carbaldehyde compound | SHINETSU CHEMICAL CO (JP) | 2000-01-05 | — | — | EP | disclosed |
| US-5519156-A | Cyclohexane carbaldehyde compounds and processes for preparing silacyclohexane-based liquid crystal compounds from the carbaldehyde | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-05-21 | — | — | US | disclosed |
| EP-0692485-A1 | Cyclohexane carbaldehyde compounds and processes for preparing silacyclohexane-based liquid crystal compounds from the carbaldehyde compound | Shin-Etsu Chemical Co., Ltd. (JP) | 1996-01-17 | — | — | EP | disclosed |