Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 7/20 | 0.48 |
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8008718 | 0.87 | KDM4E (0.46) | KDM4EHPGDKDM1AHSD11B1NPC1 | |
| SCHEMBL8009395 | 0.85 | CYP46A1 (0.39) | KDM1AHSD17B10DHODHALDH1A1 | |
| SCHEMBL1495477 | 0.82 | HPGD (0.45) | KDM4EHPGDKDM1ANPC1RAB9A | |
| SCHEMBL1495462 | 0.81 | HPGD (0.55) | KDM4EHPGDKDM1ANPC1RAB9A | |
| SCHEMBL2760988 | 0.80 | HPGD (0.58) | KDM4EHPGDKDM1ANPC1RAB9A | |
| SCHEMBL16418278 | 0.80 | HPGD (0.58) | KDM4EHPGDKDM1ANPC1RAB9A | |
| SCHEMBL2761212 | 0.79 | DHODH (0.52) | KDM4EHPGDKDM1ANPC1RAB9A | |
| SCHEMBL27967936 | 0.77 | PLA2G7 (0.61) | HPGDNPC1RAB9AKMT2AMAPK1 | |
| SCHEMBL8005875 | 0.76 | TDP1 (0.44) | KDM4EHPGDNPC1RAB9AMAPK1 | |
| SCHEMBL1495746 | 0.75 | HPGD (0.48) | KDM4EHPGDNPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009110985-A2 | AMIDE COMPOUNDS, COMPOSITIONS AND USES THEREOF | RENOVIS, INC. (US) | 2009-09-11 | — | — | WO | disclosed |