Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | PAK4 | O96013 | 1/20 | 0.35 |
| ▸ | CSF1R | P07333 | 1/20 | 0.35 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
| ▸ | GRK5 | P34947 | 1/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.35 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.35 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.35 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.35 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.35 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.35 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8009410 | 0.79 | KDM4E (0.43) | KDM4EALDH1A1MAP4K4PAK4CSF1R | |
| SCHEMBL8012335 | 0.78 | MAP4K4 (0.55) | KDM4EALDH1A1MAP4K4PAK4CSF1R | |
| SCHEMBL8003726 | 0.78 | JAK2 (0.53) | F2RL3KDM4EALDH1A1SCN5AMAP4K4 | |
| SCHEMBL8007477 | 0.75 | NPC1 (0.42) | KDM4EALDH1A1MAP4K4PAK4CSF1R | |
| SCHEMBL7997517 | 0.72 | KDM4E (0.52) | KDM4EALDH1A1ADORA1ADORA2AMAPT | |
| SCHEMBL18615178 | 0.72 | JAK2 (0.62) | F2RL3GRM2PTK2ROCK1NPSR1 | |
| SCHEMBL8912927 | 0.64 | KDM4E (0.45) | KDM4EALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL26119457 | 0.63 | MAP4K4 (0.43) | SCN5AGRM2MAP4K4ROCK1ADORA1 | |
| SCHEMBL8009917 | 0.62 | KDM4E (0.43) | KDM4EALDH1A1MAP4K4PAK4CSF1R | |
| SCHEMBL3705440 | 0.62 | AKT1 (0.47) | ALDH1A1PTK2ADORA1ADORA2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000009508-A1 | TRIAZOLOPYRIMIDINE DERIVATIVES | NIHON BAYER AGROCHEM K.K. (DE) | 2000-02-24 | — | — | WO | disclosed |