Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8010106 | 0.91 | PPARG (0.70) | PPARGPPARA | |
| SCHEMBL8009934 | 0.88 | PPARG (0.49) | PPARGPPARA | |
| SCHEMBL7826457 | 0.82 | PPARG (0.83) | PPARGPPARA | |
| SCHEMBL4865298 | 0.82 | PPARG (0.83) | PPARGPPARA | |
| SCHEMBL8007300 | 0.82 | PPARG (0.73) | PPARGPPARA | |
| SCHEMBL7998098 | 0.80 | PPARG (0.56) | PPARGPPARA | |
| SCHEMBL7825493 | 0.80 | PPARG (0.73) | PPARGPPARA | |
| SCHEMBL9267167 | 0.78 | PPARG (0.86) | PPARGPPARA | |
| SCHEMBL10211510 | 0.78 | PPARG (0.86) | PPARGPPARA | |
| SCHEMBL9270271 | 0.77 | PPARG (0.76) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6166049-A | Use of an antagonist of PPARα and PPARγ for the treatment of syndrome X | SMITHKLINE BEECHAM P.L.C. (GB) | 2000-12-26 | — | — | US | disclosed |